Nafcillin: Difference between revisions
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'''Nafcillin sodium''' is a [[narrow-spectrum antibiotic|narrow spectrum]] [[beta-lactam antibiotic]] of the [[penicillin]] class. As a [[beta-lactamase]]-resistant penicillin, it is used to treat [[infections]] caused by [[Gram-positive]] [[bacteria]], particularly [[species]] of [[Staphylococci]], that are [[antibiotic resistance|resistant]] to other penicillins. | '''Nafcillin sodium''' is a [[narrow-spectrum antibiotic|narrow spectrum]] [[beta-lactam antibiotic]] of the [[penicillin]] class. As a [[beta-lactamase]]-resistant penicillin, it is used to treat [[infections]] caused by [[Gram-positive]] [[bacteria]], particularly [[species]] of [[Staphylococci]], that are [[antibiotic resistance|resistant]] to other penicillins. | ||
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Revision as of 14:10, 20 August 2012
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| Clinical data | |
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| Routes of administration | IM, IV |
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| Protein binding | 90% |
| Metabolism | <30% hepatic |
| Excretion | Biliary and renal |
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| CAS Number | |
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C21H22N2O5S |
| Molar mass | 414.476 g/mol |
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Ongoing Trials on Nafcillin at Clinical Trials.gov Clinical Trials on Nafcillin at Google
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US National Guidelines Clearinghouse on Nafcillin
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Patient resources on Nafcillin Discussion groups on Nafcillin Directions to Hospitals Treating Nafcillin Risk calculators and risk factors for Nafcillin
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Nafcillin sodium is a narrow spectrum beta-lactam antibiotic of the penicillin class. As a beta-lactamase-resistant penicillin, it is used to treat infections caused by Gram-positive bacteria, particularly species of Staphylococci, that are resistant to other penicillins.
Side effects
As with all penicillins, serious life-threatening allergic reactions can occur.
Milder side effects include:
- Nausea and vomiting
- Diarrhea, often due to suppression of normal gastrointestinal bacteria. Occasionally, this leads to a more serious super-infection with an organism like Clostridium difficile
- Abdominal pain
- Yeast infections (thrush) affecting the mouth and tongue or vagina
- Pages with script errors
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- ECHA InfoCard ID from Wikidata
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- Articles without UNII source
- Drugs missing an ATC code
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Beta-lactam antibiotics