Teplizumab: Difference between revisions
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'''Teplizumab''' is a [[monoclonal antibody]] which it is used as an [[immunosuppressive drug]]. It is a humanized Fc-engineered monoclonal antibody also known as MGA031 and hOKT3γ1(Ala-Ala)<ref>Woodle, E.S., Bluestone, J., Zivin, R., Jolliffe, L., Auger, J., Xu, D., and J. Thistlethwaite. "Humanized, nonmitogenic OKT3 antibody, huOKT3 gamma(Ala-Ala): initial clinical experience." (1998) [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=9636555 Transplant Proc. 30:1369-1370]</ref><ref>Brown, W.M. "Anti-CD3 antibody MacroGenics Inc." (2006) [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16625825 Curr Opin Investig Drugs, 74:381-8.]</ref>. | '''Teplizumab''' is a [[monoclonal antibody]] which it is used as an [[immunosuppressive drug]]. It is a humanized Fc-engineered monoclonal antibody also known as MGA031 and hOKT3γ1(Ala-Ala)<ref>Woodle, E.S., Bluestone, J., Zivin, R., Jolliffe, L., Auger, J., Xu, D., and J. Thistlethwaite. "Humanized, nonmitogenic OKT3 antibody, huOKT3 gamma(Ala-Ala): initial clinical experience." (1998) [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=9636555 Transplant Proc. 30:1369-1370]</ref><ref>Brown, W.M. "Anti-CD3 antibody MacroGenics Inc." (2006) [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16625825 Curr Opin Investig Drugs, 74:381-8.]</ref>. | ||
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Revision as of 16:43, 20 August 2012
Template:Drugbox-mab Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Teplizumab is a monoclonal antibody which it is used as an immunosuppressive drug. It is a humanized Fc-engineered monoclonal antibody also known as MGA031 and hOKT3γ1(Ala-Ala)[1][2].
References
- ↑ Woodle, E.S., Bluestone, J., Zivin, R., Jolliffe, L., Auger, J., Xu, D., and J. Thistlethwaite. "Humanized, nonmitogenic OKT3 antibody, huOKT3 gamma(Ala-Ala): initial clinical experience." (1998) Transplant Proc. 30:1369-1370
- ↑ Brown, W.M. "Anti-CD3 antibody MacroGenics Inc." (2006) Curr Opin Investig Drugs, 74:381-8.
External links
- [2] MacroGenics, Inc.
Template:Humanizedmonoclonals Template:Immunosuppressants Template:WH Template:WikiDoc Sources