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'''Terazosin''' ('''Hytrin''') is a selective [[alpha 1 antagonist]] used for treatment of symptoms of an enlarged [[prostate]] ([[benign prostatic hyperplasia|BPH]]). It also acts to lower the [[blood pressure]], and is therefore a drug of choice for men with [[hypertension]] and prostate enlargement.
'''Terazosin''' ('''Hytrin''') is a selective [[alpha 1 antagonist]] used for treatment of symptoms of an enlarged [[prostate]] ([[benign prostatic hyperplasia|BPH]]). It also acts to lower the [[blood pressure]], and is therefore a drug of choice for men with [[hypertension]] and prostate enlargement.

Revision as of 16:43, 20 August 2012

Terazosin detailed information
File:Terazosin.svg
Clinical data
ATC code
Pharmacokinetic data
Protein binding90-94%
Elimination half-life12 hours
Identifiers
CAS Number
PubChem CID
DrugBank
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC19H25N5O4
Molar mass387.433 g/mol


Terazosin (Hytrin) is a selective alpha 1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It also acts to lower the blood pressure, and is therefore a drug of choice for men with hypertension and prostate enlargement.

It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.

Most common side effects include dizziness, drowsiness, headache, constipation, loss of appetite, fatigue, nasal congestion or dry eyes, but they generally go away after only a few days of use. Therapy should always be started with a low dose to avoid first dose phenomenon.[1] Sexual side effects are rare, but may include priapism or erectile dysfunction.

References

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