Drug allergy medical therapy: Difference between revisions
Jump to navigation
Jump to search
| Line 12: | Line 12: | ||
* '''[[Epinephrine]]''' - the treatment of choice in [[anaphylaxis]] is epinephrine, administered through intramuscular injection in the thigh. | * '''[[Epinephrine]]''' - the treatment of choice in [[anaphylaxis]] is epinephrine, administered through intramuscular injection in the thigh. | ||
* '''[[Corticosteroids]]''' - corticosteroids may be used systemically in severe reactions, but in the case of [[anaphylaxis]] it should be noted that [[epinephrine]] must be given, and it must be given before corticosteroids. | * '''[[Corticosteroids]]''' - corticosteroids may be used systemically in severe reactions, but in the case of [[anaphylaxis]] it should be noted that [[epinephrine]] must be given, and it must be given before corticosteroids. | ||
* '''[[Intensive care unit]] or | * '''[[Intensive care unit]] or burn unit''' - severe drug reactions such as [[Stevens-Johnson syndrome]] and [[toxic epidermal necrolysis]] are best treated in an intensive care unit or a burn unit setting, due to the special management required for such great amounts of insensible water loss from skin damage. <ref name="pmid22165859">{{cite journal| author=Warrington R, Silviu-Dan F| title=Drug allergy. | journal=Allergy Asthma Clin Immunol | year= 2011 | volume= 7 Suppl 1 | issue= | pages= S10 | pmid=22165859 | doi=10.1186/1710-1492-7-S1-S10 | pmc=PMC3245433 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22165859 }} </ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 20:21, 20 August 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Charmaine Patel, M.D. [2]
|
Drug Allergy |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Drug allergy medical therapy On the Web |
|
American Roentgen Ray Society Images of Drug allergy medical therapy |
|
Risk calculators and risk factors for Drug allergy medical therapy |
Overview
General Management Strategies
- Discontinuation of the allergen - The most effective strategy for treating or managing any type of allergy, is the immediate avoidance and discontinuation of the offending agent. When choosing drug therapy, alternative medications with unrelated chemical structures should be substituted for the chosen medication that has been known to cause allergy. Cross-reactivity of certain medications needs to be taken into account when selecting a treatment option. [1]
- Supportive/ symptomatic therapy - topical steroids and antihistamines are useful for cutaneous symptoms.
- Epinephrine - the treatment of choice in anaphylaxis is epinephrine, administered through intramuscular injection in the thigh.
- Corticosteroids - corticosteroids may be used systemically in severe reactions, but in the case of anaphylaxis it should be noted that epinephrine must be given, and it must be given before corticosteroids.
- Intensive care unit or burn unit - severe drug reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis are best treated in an intensive care unit or a burn unit setting, due to the special management required for such great amounts of insensible water loss from skin damage. [2]
References
- ↑ Khan DA, Solensky R (2010). "Drug allergy". J Allergy Clin Immunol. 125 (2 Suppl 2): S126–37. doi:10.1016/j.jaci.2009.10.028. PMID 20176256.
- ↑ Warrington R, Silviu-Dan F (2011). "Drug allergy". Allergy Asthma Clin Immunol. 7 Suppl 1: S10. doi:10.1186/1710-1492-7-S1-S10. PMC 3245433. PMID 22165859.