Brugada syndrome electrocardiogram: Difference between revisions
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In some cases, the disease can be detected by observing characteristic patterns on an [[electrocardiogram]], which may be present all the time, or might be elicited by the administration of particular drugs (e.g., Class IC antiarrythmic drugs that blocks sodium channels and causing appearance of ECG abnormalities - [[ajmaline]], [[flecainide]]) or resurface spontaneously due to as yet unclarified triggers. The pattern seen on the ECG is persistent ST elevations in the electrocardiographic leadsV<sub>1</sub>-V<sub>3</sub> with a [[right bundle branch block]] ([[RBBB]]) appearance with or without the terminal S waves in the lateral leads that are associated with a typical [[RBBB]]. A prolongation of the [[PR interval]] (a conduction disturbance in the heart) is also frequently seen.The electrocardiogram can fluctuate over time, depending on the autonomic balance and the administration of antiarrhythmic drugs. Adrenergic stimulation decreases the [[ST segment]] elevation, while vagal stimulation worsens it. (There is a case report of a patient who died while shaving, presumed due to the vagal stimulation of the carotid sinus massage!) The administration of class Ia, Ic and III drugs increases the [[ST segment]] elevation, and also fever. Exercise decreases [[ST segment]] elevation in some patients but increases it in others (after exercise when the body temperature has risen). The changes in heart rate induced by atrial pacing are accompanied by changes in the degree of [[ST segment]] elevation. When the heart rate decreases, the [[ST segment]] elevation increases and when the heart rate increases the [[ST segment]] elevation decreases. However, the contrary can also be observed. | In some cases, the disease can be detected by observing characteristic patterns on an [[electrocardiogram]], which may be present all the time, or might be elicited by the administration of particular drugs (e.g., Class IC antiarrythmic drugs that blocks sodium channels and causing appearance of ECG abnormalities - [[ajmaline]], [[flecainide]]) or resurface spontaneously due to as yet unclarified triggers. The pattern seen on the ECG is persistent ST elevations in the electrocardiographic leadsV<sub>1</sub>-V<sub>3</sub> with a [[right bundle branch block]] ([[RBBB]]) appearance with or without the terminal S waves in the lateral leads that are associated with a typical [[RBBB]]. A prolongation of the [[PR interval]] (a conduction disturbance in the heart) is also frequently seen.The electrocardiogram can fluctuate over time, depending on the autonomic balance and the administration of antiarrhythmic drugs. Adrenergic stimulation decreases the [[ST segment]] elevation, while vagal stimulation worsens it. (There is a case report of a patient who died while shaving, presumed due to the vagal stimulation of the carotid sinus massage!) The administration of class Ia, Ic and III drugs increases the [[ST segment]] elevation, and also fever. Exercise decreases [[ST segment]] elevation in some patients but increases it in others (after exercise when the body temperature has risen). The changes in heart rate induced by atrial pacing are accompanied by changes in the degree of [[ST segment]] elevation. When the heart rate decreases, the [[ST segment]] elevation increases and when the heart rate increases the [[ST segment]] elevation decreases. However, the contrary can also be observed. | ||
===EKG Images=== | |||
<div align="left"> | |||
<gallery heights="125" widths="125"> | |||
Image:BrugadaS.jpg|General characteristics | |||
Image:Brugada.jpg|EKG of a Patient with Brugada Syndrome | |||
Image:Brugada_lead_placement.jpg|Lead placements | |||
</gallery> | |||
</div> | |||
<div align="left"> | |||
<gallery heights="125" widths="125"> | |||
Image:Brugada_syndrome_type1_example.jpg|Brugada Type 1 | |||
Image:Brugada_syndrome_type1_example2.jpg|Brugada Type 1 | |||
Image:Brugada_syndrome_type1_example3.jpg|Brugada Type 1 | |||
</gallery> | |||
</div> | |||
<div align="left"> | |||
<gallery heights="125" widths="125"> | |||
Image:Brugada_syndrome_type1_example4.jpg|Brugada Type 1 | |||
Image:Brugada_syndrome_type1_example5.jpg|Brugada Type 1 | |||
Image:Brugada_syndrome_type1_example6.jpg|Brugada Type 1 | |||
</gallery> | |||
</div> | |||
<div align="left"> | |||
<gallery heights="125" widths="125"> | |||
Image:Brugada_syndrome_type2_example1.jpg|Brugada Type 2 | |||
Image:Brugada_syndrome_type2_example2.jpg|Brugada Type 2 | |||
Image:Brugada EKG Schema.jpg|(A) Normal electrocardiogram pattern in the precordial leads V<sub>1-3</sub>, (B) changes in Brugada syndrome (type B) | |||
</gallery> | |||
</div> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} |
Revision as of 01:17, 31 August 2012
Brugada syndrome Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Electrocardiogram
In some cases, the disease can be detected by observing characteristic patterns on an electrocardiogram, which may be present all the time, or might be elicited by the administration of particular drugs (e.g., Class IC antiarrythmic drugs that blocks sodium channels and causing appearance of ECG abnormalities - ajmaline, flecainide) or resurface spontaneously due to as yet unclarified triggers. The pattern seen on the ECG is persistent ST elevations in the electrocardiographic leadsV1-V3 with a right bundle branch block (RBBB) appearance with or without the terminal S waves in the lateral leads that are associated with a typical RBBB. A prolongation of the PR interval (a conduction disturbance in the heart) is also frequently seen.The electrocardiogram can fluctuate over time, depending on the autonomic balance and the administration of antiarrhythmic drugs. Adrenergic stimulation decreases the ST segment elevation, while vagal stimulation worsens it. (There is a case report of a patient who died while shaving, presumed due to the vagal stimulation of the carotid sinus massage!) The administration of class Ia, Ic and III drugs increases the ST segment elevation, and also fever. Exercise decreases ST segment elevation in some patients but increases it in others (after exercise when the body temperature has risen). The changes in heart rate induced by atrial pacing are accompanied by changes in the degree of ST segment elevation. When the heart rate decreases, the ST segment elevation increases and when the heart rate increases the ST segment elevation decreases. However, the contrary can also be observed.
EKG Images
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Brugada Type 2
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Brugada Type 2
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(A) Normal electrocardiogram pattern in the precordial leads V1-3, (B) changes in Brugada syndrome (type B)