Glomerulonephritis pathophysiology: Difference between revisions
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Created page with "__NOTOC__ {{CMG}} {{Glomerulonephritis}} ==Overview== ==Pathophysiology== ==References== {{reflist|2}} {{WH}} {{WS}}" |
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==Overview== | ==Overview== | ||
==Pathophysiology== | ==Pathophysiology== | ||
===Histopathology==== | |||
The majority of glomeruli present "crescents". Formation of crescents is initiated by passage of fibrin into the Bowman space as a result of increased permeability of glomerular basement membrane. Fibrin stimulates the proliferation of parietal cells of Bowman capsule, and an influx of [[monocyte]]s. Rapid growing and fibrosis of crescents compresses the capillary loops and decreases the Bowman space which leads to renal failure within weeks or months. | |||
[http://www.peir.net Images shown below are courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] | |||
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image:Acute GN 1.jpg|Glomerulonephritis: Micro H&E med mag; an excellent example of AGN with many neutrophils | |||
image:Acute GN 2.jpg|Acute Glomerulonephritis: Micro H&E high mag; an excellent example of acute exudative glomerulonephritis. | |||
</gallery> | |||
</div> | |||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Revision as of 14:25, 31 August 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Glomerulonephritis Main page |
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Overview
Pathophysiology
Histopathology=
The majority of glomeruli present "crescents". Formation of crescents is initiated by passage of fibrin into the Bowman space as a result of increased permeability of glomerular basement membrane. Fibrin stimulates the proliferation of parietal cells of Bowman capsule, and an influx of monocytes. Rapid growing and fibrosis of crescents compresses the capillary loops and decreases the Bowman space which leads to renal failure within weeks or months.
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Glomerulonephritis: Micro H&E med mag; an excellent example of AGN with many neutrophils -
Acute Glomerulonephritis: Micro H&E high mag; an excellent example of acute exudative glomerulonephritis.
