Amanullinic acid: Difference between revisions
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Latest revision as of 14:18, 4 September 2012
File:Amanullinic acid structure.png | |
File:Amanullinic acid 3 dimensional.png | |
Names | |
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Other names
1-L-Aspartic acid-3-isoleucine-alpha-amanitin
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Identifiers | |
3D model (JSmol)
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ECHA InfoCard | Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). |
PubChem CID
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Properties | |
C39H53N9O13S | |
Molar mass | 887.96 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
WikiDoc Resources for Amanullinic acid |
Articles |
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Most recent articles on Amanullinic acid Most cited articles on Amanullinic acid |
Media |
Powerpoint slides on Amanullinic acid |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Amanullinic acid at Clinical Trials.gov Trial results on Amanullinic acid Clinical Trials on Amanullinic acid at Google
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Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Amanullinic acid NICE Guidance on Amanullinic acid
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Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Amanullinic acid Discussion groups on Amanullinic acid Patient Handouts on Amanullinic acid Directions to Hospitals Treating Amanullinic acid Risk calculators and risk factors for Amanullinic acid
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Healthcare Provider Resources |
Causes & Risk Factors for Amanullinic acid |
Continuing Medical Education (CME) |
International |
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Business |
Experimental / Informatics |
Amanullinic acid is a cyclic nonribosomal peptide. It is an amatoxin, all of which are found in several members of the Amanita genus of mushrooms. The oral LD50 of amanullinic acid is approximately 20 mg/kg in mice,[1] however it is reported to be non-toxic in humans.
Toxicology
Like other amatoxins, amanullinic acid is an inhibitor of RNA polymerase II.
See also
References
- ↑ T. Wieland and Faulstich H. (1978). "Amatoxins, Phallotoxins, Phallolysin, and Antamanide: the Biologically Active Components of Poisonous Amanita Mushrooms". CRC Critical Reviews in Biochemistry. 5: 185. doi:10.3109/10409237809149870.
External links
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- Peptides
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