Chronic cholecystitis causes: Difference between revisions
Created page with "{{CMG}} {{Cholecystitis}} ==Overview== ==Causes== Cholecystitis is often caused by cholelithiasis (the presence of choleliths, or gallstones, in the [[gallbladde..." |
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==Causes== | ==Causes== | ||
Cholecystitis is often caused by [[cholelithiasis]] (the presence of [[cholelith]]s, or [[gallstone]]s, in the [[gallbladder]]), with [[cholelith]]s most commonly blocking the cystic duct directly. This leads to to [[inspissation]] of [[bile]], bile [[stasis (medicine)|stasis]] | Cholecystitis is often caused by [[cholelithiasis]] (the presence of [[cholelith]]s, or [[gallstone]]s, in the [[gallbladder]]), with [[cholelith]]s most commonly blocking the cystic duct directly. This leads to to [[inspissation]] of [[bile]], bile [[stasis (medicine)|stasis]] and secondary infection by gut organisms, predominantly ''E coli'' and Bacteroides species. | ||
The [[gallbladder]]'s wall becomes inflamed. Extreme cases may result in [[necrosis]] and [[rupture]]. Inflammation often spreads to its outer covering, thus irritating surrounding structures such as the diaphragm and bowel. | The [[gallbladder]]'s wall becomes inflamed. Extreme cases may result in [[necrosis]] and [[rupture]]. Inflammation often spreads to its outer covering, thus irritating surrounding structures such as the diaphragm and bowel. | ||
Less commonly, in debilitated and trauma patients, the [[ | Less commonly, in debilitated and trauma patients, the [[gall bladder]] may become inflamed and infected in the absence of [[cholelithiasis]], and is known as acute acalculous cholecystitis. | ||
Stones in the [[ | Stones in the [[gall bladder]] may not cause obstruction and the accompanying acute attack. The patient might develop a chronic, low-level inflammation which leads to a [[chronic cholecystitis]], where the gallbladder is fibrotic and calcified. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 17:59, 4 September 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Causes
Cholecystitis is often caused by cholelithiasis (the presence of choleliths, or gallstones, in the gallbladder), with choleliths most commonly blocking the cystic duct directly. This leads to to inspissation of bile, bile stasis and secondary infection by gut organisms, predominantly E coli and Bacteroides species.
The gallbladder's wall becomes inflamed. Extreme cases may result in necrosis and rupture. Inflammation often spreads to its outer covering, thus irritating surrounding structures such as the diaphragm and bowel.
Less commonly, in debilitated and trauma patients, the gall bladder may become inflamed and infected in the absence of cholelithiasis, and is known as acute acalculous cholecystitis.
Stones in the gall bladder may not cause obstruction and the accompanying acute attack. The patient might develop a chronic, low-level inflammation which leads to a chronic cholecystitis, where the gallbladder is fibrotic and calcified.