Cirrhosis cost-effectiveness of therapy: Difference between revisions
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==Cost-effectiveness of Therapy== | ==Cost-effectiveness of Therapy== | ||
===Management of adult patients with ascites due to cirrhosis=== | ===Management of adult patients with ascites due to cirrhosis=== | ||
* Abdominal paracentesis with appropriate ascitic fluid analysis is probably the most rapid and cost-effective method of diagnosing the cause of ascites. | * [[Abdominal]] [[paracentesis]] with appropriate [[ascitic fluid]] analysis is probably the most rapid and cost-effective method of diagnosing the cause of ascites. | ||
*The risks and costs of prophylactic transfusions may exceed the benefit. | *The risks and costs of prophylactic transfusions may exceed the benefit. | ||
* Intravenous ciprofloxacin followed by oral administration of this drug was found to be more cost-effective compared to intravenous ceftazidime in a randomized trial in patients who had not received quinolone prophylaxis. | * [[Intravenous]] [[ciprofloxacin]] followed by oral administration of this drug was found to be more cost-effective compared to intravenous ceftazidime in a randomized trial in patients who had not received [[quinolone]] prophylaxis. | ||
* Selective intestinal decontamination with norfloxacin or trimethoprim/sulfamethoxazole in patients with prior spontaneous bacterial peritonitis (SBP) or low-protein ascitic fluid does appear to be cost-effective | * Selective intestinal decontamination with [[norfloxacin]] or [[trimethoprim/sulfamethoxazole]] in patients with prior [[spontaneous bacterial peritonitis]] (SBP) or low-[[protein]] ascitic fluid does appear to be cost-effective | ||
==Reference== | ==Reference== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 16:17, 6 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-In-Chief: Ujjwal Rastogi, M.B.B.S. [2]
Overview
According to a report from The National Center for Health Statistics, Cirrhosis and chronic liver disease accounted for more than 25,000 deaths and 373,000 hospital discharges in the United States in 1998.
Cost-effectiveness of Therapy
Management of adult patients with ascites due to cirrhosis
- Abdominal paracentesis with appropriate ascitic fluid analysis is probably the most rapid and cost-effective method of diagnosing the cause of ascites.
- The risks and costs of prophylactic transfusions may exceed the benefit.
- Intravenous ciprofloxacin followed by oral administration of this drug was found to be more cost-effective compared to intravenous ceftazidime in a randomized trial in patients who had not received quinolone prophylaxis.
- Selective intestinal decontamination with norfloxacin or trimethoprim/sulfamethoxazole in patients with prior spontaneous bacterial peritonitis (SBP) or low-protein ascitic fluid does appear to be cost-effective