Inappropriate sinus tachycardia: Difference between revisions

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==Diagnosis==
==Diagnosis==
===Diagnostic Criteria===
No formal diagnostic criteria exist. A diagnosis of Inappropriate sinus tachycardia is primarily a diagnosis of exclusion and the following must be observed:
*Exclusion of all other causes of [[sinus tachycardia]]
*Common forms of [[supraventricular tachycardia]] (SVT) must be excluded
*Normal [[P wave]] morphology
*A resting [[sinus tachycardia]] is usually (but not always) present
*A nocturnal reduction in [[heart rate]] from over 100 beats per minute to 80 - 90 beats per minute
*There is an inappropriate [[heart rate]] response on exertion so that the heart rate accelerates to 140 - 150 beats per minute with minimal exertion.
*The mean [[heart rate]] during 24 hrs of monitoring is > 95 bpm
*Symptoms are documented to be due to [[tachycardia]]
*[[Hypotension]] may occasionally be observed
*[[Syncope]] ([[fainting]]) is occasionally reported
=== Symptoms ===
=== Symptoms ===
Symptoms reported by patients vary in frequency and severity. Symptoms associated with Inappropriate sinus tachycardia include:
Symptoms reported by patients vary in frequency and severity. Symptoms associated with Inappropriate sinus tachycardia include:

Revision as of 12:38, 10 September 2012

Inappropriate sinus tachycardia Microchapters

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Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Inappropriate Sinus Tachycardia from other Medical Conditions

Epidemiology and Demographics

Diagnosis

Diagnostic Criteria

History and Symptoms

Electrocardiogram

Treatment

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: IST; chronic nonparoxysmal sinus tachycardia

Overview

Historical Perspective

Pathophysiology

Epidemiology and Demographics

Differentiating Inappropriate Sinus Tachycardia from other Medical Conditions

Differentiating Inappropriate Sinus Tachycardia from other Supraventricular Arrhythmias

Diagnosis

Symptoms

Symptoms reported by patients vary in frequency and severity. Symptoms associated with Inappropriate sinus tachycardia include:

Treatment

Treatments in the form of pharmacological therapy or catheter ablation are available, although it is currently difficult to treat successfully.

Beta-blockers

In so far as the pathophysiology of IST involves abnormal sensitivity to adrenaline, betaa-blockers can be helpful.

Calcium Channel Blockers

Although calcium channel blockers slow conduction through the AV node, they have been marginally effective in the treatment of IST.

Ivabradine

A new selective sinus node inhibitor Ivabradine is also being used to treat IST.

Treatments Related to Dysautonomia and POTS

In so far as the underlying pathophysiology may involve a dysautonomia and features of Postural orthostatic tachycardia syndrome (POTS), some therapies more commonly used to treat these disorders have been tried:

Fludrocortisone (Florinef)

POTS and dysautonomia have been associated with decreases in blood volume, and this drug promotes sodium retention.

Midodrine

Midodrine increases vasoconstriction, and prevents falls in blood pressure.

Serotonin-reuptake inhibitors (SSRIs)

SSRIs have proven effective in treating some patients with dysautonomia.

Catheter Ablation

Invasive treatments include forms of Catheter ablation has gained favor among electrophysiologists in the treatment of IST.

Sinus Node Modification

This procedure involves selective ablation of the sinus node. The rhythm reoccurs in 80% of cases.

Complete Sinus Node Ablation

This procedure requires implantation of a Permanent Artificial pacemaker)

AV Node Ablation

In cases resistant to sinus node ablation, AV node ablation with creation of an iatrogenic complete heart block, may be neccessary. This procedure requires implantation of a permanent artificial pacemaker.

See also

References



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