Nodular melanoma: Difference between revisions
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[[Image:NodularMelanomaEvolution.jpg|thumb|alt=Evolution of a 4mm nodular melanoma.|Evolution of a 4mm nodular melanoma.]] | [[Image:NodularMelanomaEvolution.jpg|thumb|left|alt=Evolution of a 4mm nodular melanoma.|Evolution of a 4mm nodular melanoma.]] | ||
'''Nodular melanoma''' (NM) is the most aggressive form of [[melanoma]]. It grows in vertical direction from the outset and grows very fast (months). Nodular melanoma has no known precursor. It is a small black, or if amelanotic, pink nodule that simply enlarges. The lesions tend to bleed. | '''Nodular melanoma''' (NM) is the most aggressive form of [[melanoma]]. It grows in vertical direction from the outset and grows very fast (months). Nodular melanoma has no known precursor. It is a small black, or if amelanotic, pink nodule that simply enlarges. The lesions tend to bleed. | ||
Revision as of 17:11, 10 September 2012
Template:DiseaseDisorder infobox
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Nodular melanoma (NM) is the most aggressive form of melanoma. It grows in vertical direction from the outset and grows very fast (months). Nodular melanoma has no known precursor. It is a small black, or if amelanotic, pink nodule that simply enlarges. The lesions tend to bleed.
Pathophysiology
Microscopic Pathology
The microscopic hallmarks are:
- Dome-shaped at low power
- Epidermis thin or normal
- Dermal nodule of melanocytes with a 'pushing' growth pattern
- No "radial growth phase"