Pheochromocytoma pathophysiology

Pheochromocytoma Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Pathophysiology

Traditionally it is known as the "10% tumor":

• bilateral disease is present in approximately 10% of patients
• approximately 10% of tumours are malignant
• approximately 10% are located in chromaffin tissue outside of the adrenal gland
• Approximately 10% arise in childhood
• Approximately 10% are familial
• Approximately 10% recur after being resected
• Approximately 10% patients do not have hypertension (Campbell's Urology)

Images

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  Micrograph of pheochromocytoma.

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  Micrograph of pheochromocytoma.

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  Micrograph of pheochromocytoma.

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  Bilateral pheochromocytoma in MEN2. Gross image.