Myelodysplastic syndrome differential diagnosis: Difference between revisions
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The differential diagnosis is that of [[anemia]], [[thrombocytopenia]], and/or [[leukopenia]]. Usually, the elimination of known [[etiologies]] of [[cytopenias]], along with a dysplastic bone marrow, is required to diagnose a myelodysplastic syndrome. | The differential diagnosis is that of [[anemia]], [[thrombocytopenia]], and/or [[leukopenia]]. Usually, the elimination of known [[etiologies]] of [[cytopenias]], along with a dysplastic bone marrow, is required to diagnose a myelodysplastic syndrome. | ||
== | ==Differenting Myeloproliferative disease from other Diseases== | ||
Differential Diagnosis (for dysplasia) | Differential Diagnosis (for dysplasia) | ||
* Arsenic, Lead, Benzene, Xylene, petroleum, Agent Orange (Vietnam Veterans). | * Arsenic, Lead, Benzene, Xylene, petroleum, Agent Orange (Vietnam Veterans). |
Revision as of 16:50, 11 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The differential diagnosis is that of anemia, thrombocytopenia, and/or leukopenia. Usually, the elimination of known etiologies of cytopenias, along with a dysplastic bone marrow, is required to diagnose a myelodysplastic syndrome.
Differenting Myeloproliferative disease from other Diseases
Differential Diagnosis (for dysplasia)
- Arsenic, Lead, Benzene, Xylene, petroleum, Agent Orange (Vietnam Veterans).
- Congenital Dyserythropoietic anemia
- HIV
- Vitamin B12 / folate
- Parvovirus
- Alcohol abuse
- Prior chemotherapy (eg. melphalan, mustard, chlorambucil, busulfan, cyclophosphamide).
- Radiation (with or without chemotherapy).