Medulloblastoma natural history: Difference between revisions
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{{Medulloblastoma}} | {{Medulloblastoma}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | |||
==Natural History== | |||
==Complications== | |||
==Prognosis== | ==Prognosis== | ||
Treatment begins with maximal resection of the tumor. The addition of ''radiation'' to the entire neuraxis and ''chemotherapy'' may increase the disease-free survival. This combination may permit a 5 year survival in more than 80% of cases. The presence of desmoplastic features such as connective tissue formation offers a better prognosis. Prognosis is worse if child is less than 3 years old, inadequate degree of resection, or if presence of any CSF, spinal, supratentorial or systemic spread. | Treatment begins with maximal resection of the tumor. The addition of ''radiation'' to the entire neuraxis and ''chemotherapy'' may increase the disease-free survival. This combination may permit a 5 year survival in more than 80% of cases. The presence of desmoplastic features such as connective tissue formation offers a better prognosis. Prognosis is worse if child is less than 3 years old, inadequate degree of resection, or if presence of any CSF, spinal, supratentorial or systemic spread. | ||
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Revision as of 18:05, 13 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
Complications
Prognosis
Treatment begins with maximal resection of the tumor. The addition of radiation to the entire neuraxis and chemotherapy may increase the disease-free survival. This combination may permit a 5 year survival in more than 80% of cases. The presence of desmoplastic features such as connective tissue formation offers a better prognosis. Prognosis is worse if child is less than 3 years old, inadequate degree of resection, or if presence of any CSF, spinal, supratentorial or systemic spread.
Increase intracranial pressure may be controlled with corticosteroids or a ventriculoperitoneal shunt