Langerhans cell histiocytosis medical therapy: Difference between revisions
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Varun Kumar (talk | contribs) Created page with "{{Langerhans cell histiocytosis}} {{CMG}} ==Treatment== Treatment is guided by extent of disease. <br />Solitary bone lesion may be amenable through excision or limited radia..." |
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{{Langerhans cell histiocytosis}} | {{Langerhans cell histiocytosis}} | ||
{{CMG}} | {{CMG}} | ||
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==Overview== | |||
==Treatment== | ==Treatment== | ||
Treatment is guided by extent of disease. | Treatment is guided by extent of disease. | ||
*Solitary bone lesion may be amenable through excision or limited radiation. However systemic disease often require chemotherapy. | |||
*Use of systemic steroid is common, singly or adjunct to chemotherapy. Local steroid cream is applied to skin lesions. | |||
*Endocrine deficiency often require lifelong suppliment e.g. desmopressin for diabates insipidus which can be applied as nasal drop. | |||
*[[Chemotherapeutic]] agents such as [[alkylating antineoplastic agent|alkylating agents]], [[antimetabolite]]s, [[vinca alkaloids]] either singly or in combination can lead to complete remission in diffuse disease. | |||
==References== | ==References== |
Revision as of 19:49, 13 September 2012
Langerhans cell histiocytosis Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Treatment
Treatment is guided by extent of disease.
- Solitary bone lesion may be amenable through excision or limited radiation. However systemic disease often require chemotherapy.
- Use of systemic steroid is common, singly or adjunct to chemotherapy. Local steroid cream is applied to skin lesions.
- Endocrine deficiency often require lifelong suppliment e.g. desmopressin for diabates insipidus which can be applied as nasal drop.
- Chemotherapeutic agents such as alkylating agents, antimetabolites, vinca alkaloids either singly or in combination can lead to complete remission in diffuse disease.