Acute promyelocytic leukemia differential diagnosis: Difference between revisions
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Acute promyelocytic leukemia can be distinguished from other types of AML based on morphologic examination of a [[bone marrow biopsy]] or aspirate. Definitive diagnosis requires testing for the ''RARα'' fusion gene. This may be done by [[polymerase chain reaction]] (PCR), [[fluorescent in situ hybridization]] (FISH), or conventional [[cytogenetics]] of peripheral blood or bone marrow. | Acute promyelocytic leukemia can be distinguished from other types of AML based on morphologic examination of a [[bone marrow biopsy]] or aspirate. Definitive diagnosis requires testing for the ''RARα'' fusion gene. This may be done by [[polymerase chain reaction]] (PCR), [[fluorescent in situ hybridization]] (FISH), or conventional [[cytogenetics]] of peripheral blood or bone marrow. | ||
==References== | ==References== | ||
Revision as of 15:30, 17 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Differentiating Acute promyelocytic meukemia from other Diseases
Acute promyelocytic leukemia can be distinguished from other types of AML based on morphologic examination of a bone marrow biopsy or aspirate. Definitive diagnosis requires testing for the RARα fusion gene. This may be done by polymerase chain reaction (PCR), fluorescent in situ hybridization (FISH), or conventional cytogenetics of peripheral blood or bone marrow.