Adrenolipoma: Difference between revisions
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== Overview == | == Overview == | ||
Adrenolipomas are benign tumors histologically consisting of fat and bone marrow in varying proportions. These tumors are benign. In general they are hormonally inactive, small (<5 cm) and unilateral. Adrenolipomas are rare benign [[neoplasms]].They are made up of mature [[adipose tissue]] and a variable amount of [[hematopoietic]] elements. Most lesions are small and asymptomatic. They are usually discovered incidentally at [[autopsy]] or on imaging studies performed for other reasons. Most tumors are unilateral but show no predilection to one particular side. Tumor size varies from several millimeters to more than 30 cm. | Adrenolipomas are benign tumors histologically consisting of fat and bone marrow in varying proportions. These tumors are benign. In general they are hormonally inactive, small (<5 cm) and unilateral. Adrenolipomas are rare benign [[neoplasms]].They are made up of mature [[adipose tissue]] and a variable amount of [[hematopoietic]] elements. Most lesions are small and asymptomatic. They are usually discovered incidentally at [[autopsy]] or on imaging studies performed for other reasons. Most tumors are unilateral but show no predilection to one particular side. Tumor size varies from several millimeters to more than 30 cm. | ||
==Pathophysiology== | |||
A myelolipoma may represent a site of [[extramedullary hematopoiesis]]. The most widely accepted theory is the existence of [[metaplasia]] of the [[reticuloendothelial cells]] of blood [[capillaries]] in the [[adrenal gland]] in response to stimuli such as [[necrosis]], [[infection]], or [[stress]]. | |||
== Epidemiology and Demographics == | == Epidemiology and Demographics == | ||
Revision as of 16:20, 18 September 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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WikiDoc Resources for Adrenolipoma |
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Most recent articles on Adrenolipoma Most cited articles on Adrenolipoma |
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Ongoing Trials on Adrenolipoma at Clinical Trials.gov Clinical Trials on Adrenolipoma at Google
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US National Guidelines Clearinghouse on Adrenolipoma
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Patient resources on Adrenolipoma Discussion groups on Adrenolipoma Patient Handouts on Adrenolipoma Directions to Hospitals Treating Adrenolipoma Risk calculators and risk factors for Adrenolipoma
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Synonyms and keywords: Adrenal myelolipoma
Overview
Adrenolipomas are benign tumors histologically consisting of fat and bone marrow in varying proportions. These tumors are benign. In general they are hormonally inactive, small (<5 cm) and unilateral. Adrenolipomas are rare benign neoplasms.They are made up of mature adipose tissue and a variable amount of hematopoietic elements. Most lesions are small and asymptomatic. They are usually discovered incidentally at autopsy or on imaging studies performed for other reasons. Most tumors are unilateral but show no predilection to one particular side. Tumor size varies from several millimeters to more than 30 cm.
Pathophysiology
A myelolipoma may represent a site of extramedullary hematopoiesis. The most widely accepted theory is the existence of metaplasia of the reticuloendothelial cells of blood capillaries in the adrenal gland in response to stimuli such as necrosis, infection, or stress.
Epidemiology and Demographics
The incidence varies from 0.08-0.4% at autopsy.
Natural History
Benign. Adrenal hemorrhage is rare.
Differential Diagnosis
That of an incidentaloma.
Acknowledgements
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.