Adrenolipoma: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
A myelolipoma may represent a site of [[extramedullary hematopoiesis]]. The most widely accepted theory is the existence of [[metaplasia]] of the [[reticuloendothelial cells]] of blood [[capillaries]] in the [[adrenal gland]] in response to stimuli such as [[necrosis]], [[infection]], or [[stress]]. | A myelolipoma may represent a site of [[extramedullary hematopoiesis]]. The most widely accepted theory is the existence of [[metaplasia]] of the [[reticuloendothelial cells]] of blood [[capillaries]] in the [[adrenal gland]] in response to stimuli such as [[necrosis]], [[infection]], or [[stress]]. | ||
== Differential Diagnosis == | |||
That of an incidentaloma. | |||
== Epidemiology and Demographics == | == Epidemiology and Demographics == | ||
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== Natural History == | == Natural History == | ||
Benign. [[Adrenal hemorrhage]] is rare. | Benign. [[Adrenal hemorrhage]] is rare. | ||
==Diagnosis== | ==Diagnosis== | ||
Revision as of 16:21, 18 September 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Synonyms and keywords: Adrenal myelolipoma
Overview
Adrenolipomas are benign tumors histologically consisting of fat and bone marrow in varying proportions. These tumors are benign. In general they are hormonally inactive, small (<5 cm) and unilateral. Adrenolipomas are rare benign neoplasms.They are made up of mature adipose tissue and a variable amount of hematopoietic elements. Most lesions are small and asymptomatic. They are usually discovered incidentally at autopsy or on imaging studies performed for other reasons. Most tumors are unilateral but show no predilection to one particular side. Tumor size varies from several millimeters to more than 30 cm.
Pathophysiology
A myelolipoma may represent a site of extramedullary hematopoiesis. The most widely accepted theory is the existence of metaplasia of the reticuloendothelial cells of blood capillaries in the adrenal gland in response to stimuli such as necrosis, infection, or stress.
Differential Diagnosis
That of an incidentaloma.
Epidemiology and Demographics
The incidence varies from 0.08-0.4% at autopsy.
Natural History
Benign. Adrenal hemorrhage is rare.
Diagnosis
CT
Patient #1: CT images demonstrate a large left myelolipoma
Patient #2: CT images demonstrate a left myelolipoma with a small amount of marcoscopic fat
Acknowledgements
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.