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'''Hyperprolactinaemia''' ([[British English|BrE]]) or '''hyperprolactinemia''' ([[American English|AmE]]) is the presence of abnormally high levels of [[prolactin]] in the blood. [[Reference ranges for common blood tests|Normal levels]] are less than 580 mIU/L for women, and less than 450 mIU/L for men. | '''Hyperprolactinaemia''' ([[British English|BrE]]) or '''hyperprolactinemia''' ([[American English|AmE]]) is the presence of abnormally high levels of [[prolactin]] in the blood. [[Reference ranges for common blood tests|Normal levels]] are less than 580 mIU/L for women, and less than 450 mIU/L for men. | ||
The hormone prolactin is downregulated by [[dopamine]] and is upregulated by [[estrogen]]. A falsely high measurement may occur due to the presence of the biologically inactive [[macroprolactin]] in the serum. This can show up as high prolactin in some types of tests, but is asymptomatic.==References== | The hormone prolactin is downregulated by [[dopamine]] and is upregulated by [[estrogen]]. A falsely high measurement may occur due to the presence of the biologically inactive [[macroprolactin]] in the serum. This can show up as high prolactin in some types of tests, but is asymptomatic. | ||
==References== | |||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 15:11, 20 September 2012
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Hyperprolactinemia Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Hyperprolactinaemia (BrE) or hyperprolactinemia (AmE) is the presence of abnormally high levels of prolactin in the blood. Normal levels are less than 580 mIU/L for women, and less than 450 mIU/L for men.
The hormone prolactin is downregulated by dopamine and is upregulated by estrogen. A falsely high measurement may occur due to the presence of the biologically inactive macroprolactin in the serum. This can show up as high prolactin in some types of tests, but is asymptomatic.