Rh disease medical therapy: Difference between revisions
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'''Antenatal''' | '''Antenatal''' | ||
*Ultrasound - to detect and monitor [[hydrops fetalis]] | *Ultrasound - to detect and monitor [[hydrops fetalis]] | ||
*Quantitative analysis of maternal anti-RhD antibodies - an increasing level is a sign of fetal Rh disease | *Quantitative analysis of maternal anti-RhD antibodies - an increasing level is a sign of fetal Rh disease<ref>http://www.ncbi.nlm.nih.gov/pubmed?term=14105934</ref> | ||
*Intrauterine blood transfusion | *Intrauterine blood transfusion | ||
**Intraperitoneal transfusion - blood transfused into fetal abdomen | **Intraperitoneal transfusion - blood transfused into fetal abdomen | ||
Latest revision as of 15:00, 21 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
Antenatal
- Ultrasound - to detect and monitor hydrops fetalis
- Quantitative analysis of maternal anti-RhD antibodies - an increasing level is a sign of fetal Rh disease[1]
- Intrauterine blood transfusion
- Intraperitoneal transfusion - blood transfused into fetal abdomen
- Intravascular transfusion - blood transfused into fetal umbilical vein - This is more modern and more effective than intraperitoneal transfusion. A sample of fetal blood can be taken from the umbilical vein prior to the transfusion.
- Early delivery (usually after about 36 wks gestation)
Postnatal
- Phototherapy for neonatal jaundice in mild disease
- Exchange transfusion if the neonate has moderate or severe disease (the blood for transfusion must be less than a week old, Rh negative, ABO compatible with both the fetus and the mother, and be cross matched against the mothers serum)