Autoimmune hemolytic anemia classification: Difference between revisions
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'''Extravascular haemolysis'''<br> | '''Extravascular haemolysis'''<br> | ||
Red Blood Cells that are coated with antibodies are specifically recognised in the [[reticuloendothelial system]] and destroyed by [[macrophages]]. | Red Blood Cells that are coated with antibodies are specifically recognised in the [[reticuloendothelial system]] and destroyed by [[macrophages]]. | ||
===Subtypes=== | |||
*'''[[Warm antibody autoimmune hemolytic anemia]]''' | |||
:*Idiopathic | |||
:*[[Systemic lupus erythematosus]] | |||
:*[[Evans' syndrome]] (antiplatelet antibodies and haemolytic antibodies) | |||
:*[[Chronic lymphocytic leukemia]] | |||
:*Drugs ([[methyldopa]]) | |||
*'''Cold antibody autoimmune hemolytic anemia''' | |||
:*[[Idiopathic cold hemagglutinin syndrome]] | |||
:*[[Infectious mononucleosis]] | |||
:*[[Paroxysmal cold hemoglobinuria]] (rare) | |||
:*[[Lymphoma]] | |||
*'''Mixed-type autoimmune hemolytic anemia''' | |||
==References== | ==References== |
Revision as of 15:49, 21 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Assosciate Editor(s)-In-Chief: Prashanth Saddala M.B.B.S
Overview
Classification
Haemolysis can be intravascular or extravascular.
Intravascular haemolysis
Red blood cell lysis occurs in the circulation as a result of activation of the complement system cascade.
Extravascular haemolysis
Red Blood Cells that are coated with antibodies are specifically recognised in the reticuloendothelial system and destroyed by macrophages.
Subtypes
- Idiopathic
- Systemic lupus erythematosus
- Evans' syndrome (antiplatelet antibodies and haemolytic antibodies)
- Chronic lymphocytic leukemia
- Drugs (methyldopa)
- Cold antibody autoimmune hemolytic anemia
- Mixed-type autoimmune hemolytic anemia
References