Acute monocytic leukemia laboratory findings: Difference between revisions
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{{Acute monocytic leukemia}} | {{Acute monocytic leukemia}} | ||
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==Overview== | |||
==Laboratory Findings== | |||
*Peripheral Smear | |||
**[[Monoblasts]] can be distinguished by having a roughly circular nucleus, delicate lacy chromatin, and abundant, often basophilic cytoplasm. These cells may also have pseudopods. By contrast, promonocytes have a more convoluted nucleus, and their cytoplasm may contain metachromatic granules. | |||
*[[Monoblasts]] are typically [[Myeloperoxidase|MPO]] negative and promonocytes are [[Myeloperoxidase|MPO]] variable. Both [[monoblasts]] and promonocytes stain positive for non-specific [[esterase]] (NSE), however [[Esterase|NSE]] may often be negative. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
Revision as of 19:02, 21 September 2012
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Acute monocytic leukemia Microchapters |
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Differentiating Acute monocytic leukemia from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Acute monocytic leukemia laboratory findings On the Web |
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American Roentgen Ray Society Images of Acute monocytic leukemia laboratory findings |
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Risk calculators and risk factors for Acute monocytic leukemia laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
- Peripheral Smear
- Monoblasts can be distinguished by having a roughly circular nucleus, delicate lacy chromatin, and abundant, often basophilic cytoplasm. These cells may also have pseudopods. By contrast, promonocytes have a more convoluted nucleus, and their cytoplasm may contain metachromatic granules.
- Monoblasts are typically MPO negative and promonocytes are MPO variable. Both monoblasts and promonocytes stain positive for non-specific esterase (NSE), however NSE may often be negative.