ARVD1: Difference between revisions
Jump to navigation
Jump to search
Line 7: | Line 7: | ||
==Pathophysiology== | ==Pathophysiology== | ||
The pathogenesis of ARVD involves [[apoptosis]] with fatty and fibro-fatty infiltration of the right ventricular free wall leading to [[heart failure]] and [[ventricular arrhythmias]]. | |||
===Genetics=== | ===Genetics=== | ||
There is an [[autosomal dominant]] pattern of inheritance. This variant is due to a heterozygous mutation in the [[TGFB3]] gene ([http://omim.org/entry/190230 190230]) on chromosome 14q24. | There is an [[autosomal dominant]] pattern of inheritance. This variant is due to a heterozygous mutation in the [[TGFB3]] gene ([http://omim.org/entry/190230 190230]) on chromosome 14q24. |
Revision as of 01:10, 23 September 2012
Arrhythmogenic right ventricular dysplasia Microchapters |
Differentiating Arrhythmogenic right ventricular dysplasia from other Diseases |
---|
Diagnosis |
Treatment |
ARVD1 On the Web |
American Roentgen Ray Society Images of ARVD1 |
Directions to Hospitals Treating Arrhythmogenic right ventricular dysplasia |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Arrhythmogenic right ventricular dysplasia type 1;
Overview
Pathophysiology
The pathogenesis of ARVD involves apoptosis with fatty and fibro-fatty infiltration of the right ventricular free wall leading to heart failure and ventricular arrhythmias.
Genetics
There is an autosomal dominant pattern of inheritance. This variant is due to a heterozygous mutation in the TGFB3 gene (190230) on chromosome 14q24.