Solitary pulmonary nodule other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
==PET Scan== | ==PET Scan== | ||
Image:Malignant solitary pulmonary nodule 2.PET.jpg|After a 4 hour fast, the patient was injected with 10 mCi of 18-FDG IV and after allowing one hour for localization, transmission and emission PET data were acquired. A hypermetabolic focus can be seen in the left upper lobe corresponding to the chest x-ray abnormality. No other abnormalities are seen. The hypermetabolic nodule suggests a malignant process without metastasis. Lesions with only slight tracer uptake can be evaluated quantitatively for significance. A significant uptake value (SUV) can be calculated by dividing the mean activity in the suspicious area (mCi/ml) by the injected dose (mCi) per kilograms of body weight. Using a (SUV) of 2.5 or greater to define a malignancy, the sensitivity and specificity of 18-FDG-PET for detecting cancer in solitary pulmonary nodules greater than 1.2 cm approaches 90% with a nearly 100% specificity (1). False positives have included infectious etiologies, and sarcoid. | [[Image:Malignant solitary pulmonary nodule 2.PET.jpg|Thumb|center|After a 4 hour fast, the patient was injected with 10 mCi of 18-FDG IV and after allowing one hour for localization, transmission and emission PET data were acquired. A hypermetabolic focus can be seen in the left upper lobe corresponding to the chest x-ray abnormality. No other abnormalities are seen. The hypermetabolic nodule suggests a malignant process without metastasis. Lesions with only slight tracer uptake can be evaluated quantitatively for significance. A significant uptake value (SUV) can be calculated by dividing the mean activity in the suspicious area (mCi/ml) by the injected dose (mCi) per kilograms of body weight. Using a (SUV) of 2.5 or greater to define a malignancy, the sensitivity and specificity of 18-FDG-PET for detecting cancer in solitary pulmonary nodules greater than 1.2 cm approaches 90% with a nearly 100% specificity (1). False positives have included infectious etiologies, and sarcoid.]] | ||
==References== | ==References== |
Revision as of 14:35, 25 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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PET Scan