Pyelonephritis pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
Acute pyelonephritis is an ''exudative purulent localized inflammation'' of the renal pelvis (collecting system) and kidney. The renal parenchyma presents in the interstitium abscesses (suppurative necrosis), consisting in purulent exudate (pus): | Acute pyelonephritis is an ''exudative purulent localized inflammation'' of the renal pelvis (collecting system) and kidney. The renal [[parenchyma]] presents in the interstitium abscesses (suppurative necrosis), consisting in purulent [[exudate]] (pus): [[neutrophil]]s, [[fibrin]], cell debris and central germ colonies ([[hematoxylinophil]]s). Tubules are damaged by exudate and may contain neutrophil casts. In the early stages, glomeruli and vessels are normal.[http://www.pathologyatlas.ro/Interstitial%20Pyelonephritis1.html] Gross pathology often reveals pathognomonic radiations of [[hemorrhage]] and suppuration through the [[renal pelvis]] to the [[renal cortex]]. Chronic infections can result in [[fibrosis]] and scarring. | ||
==Microscopic Pathology== | ===Microscopic Pathology=== | ||
===Acute pyelonephritis=== | ====Acute pyelonephritis==== | ||
{{#ev:youtube|aZ2il9a63J4}} | {{#ev:youtube|aZ2il9a63J4}} | ||
===Chronic pyelonephritis=== | ====Chronic pyelonephritis==== | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Nephrology]] | |||
[[Category:Inflammations]] | |||
[[Category:Disease]] |
Revision as of 14:46, 27 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Acute pyelonephritis is an exudative purulent localized inflammation of the renal pelvis (collecting system) and kidney. The renal parenchyma presents in the interstitium abscesses (suppurative necrosis), consisting in purulent exudate (pus): neutrophils, fibrin, cell debris and central germ colonies (hematoxylinophils). Tubules are damaged by exudate and may contain neutrophil casts. In the early stages, glomeruli and vessels are normal.[2] Gross pathology often reveals pathognomonic radiations of hemorrhage and suppuration through the renal pelvis to the renal cortex. Chronic infections can result in fibrosis and scarring.
Microscopic Pathology
Acute pyelonephritis
{{#ev:youtube|aZ2il9a63J4}}
Chronic pyelonephritis
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