Pneumocystis jirovecii pneumonia medical therapy: Difference between revisions
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[[Pentamidine]] is less often used as its major limitation is the high frequency of [[side effect]]s. These include acute [[pancreatitis]], [[renal failure]], [[hepatotoxicity]], [[leukopenia]], [[rash]], [[fever]] and [[hypoglycaemia]]. | [[Pentamidine]] is less often used as its major limitation is the high frequency of [[side effect]]s. These include acute [[pancreatitis]], [[renal failure]], [[hepatotoxicity]], [[leukopenia]], [[rash]], [[fever]] and [[hypoglycaemia]]. | ||
===Guidelines=== | |||
To read about guidelines for prevention and treatment of Pneumocystis pneumonia Infections in HIV-Infected Adults and Adolescents, click [[HIV opportunistic infection pneumocystis pneumonia: prevention and treatment guidelines|'''here''']]. | |||
==References== | ==References== | ||
Revision as of 18:37, 27 September 2012
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Pneumocystis jirovecii pneumonia Microchapters |
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Differentiating Pneumocystis jirovecii pneumonia from other Diseases |
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Diagnosis |
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Treatment |
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Pneumocystis jirovecii pneumonia medical therapy On the Web |
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Risk calculators and risk factors for Pneumocystis jirovecii pneumonia medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
Antipneumocystic medication is used with concomitant steroids in order to avoid inflammation, which causes an exacerbation of symptoms about four days after treatment begins if steroids are not used. By far the most commonly used medication is a combination of trimethoprim and sulfamethoxazole (co-trimoxazole, with the tradenames Bactrim, Septrin, or Septra), but some patients are unable to tolerate this treatment due to allergies. Other medications that are used, alone or in combination, include pentamidine, trimetrexate, dapsone, atovaquone, primaquine, and clindamycin. Treatment is usually for a period of about 21 days.
Pentamidine is less often used as its major limitation is the high frequency of side effects. These include acute pancreatitis, renal failure, hepatotoxicity, leukopenia, rash, fever and hypoglycaemia.
Guidelines
To read about guidelines for prevention and treatment of Pneumocystis pneumonia Infections in HIV-Infected Adults and Adolescents, click here.