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| {{SK}} ketoacidemia; | | {{SK}} ketoacidemia; |
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| ==Causes==
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| ===Starvation and Fasting===
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| It can also occur with people undergoing hunger strikes, fasting over 3 days, or people starving to death as the body is forced to break down fat for sustenance due to their lack of outside nutrition.
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| ===Diabetic Ketoacidosis===
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| In [[diabetic]] patients, ketoacidosis is usually accompanied by [[insulin]] deficiency, [[hyperglycemia]], and [[dehydration]]. Since insulin is required to absorb [[glucose]] from the blood, its deficiency results in an energy crisis, fatty acid metabolism, and production of ketone bodies. Hyperglycemia results in glucose overloading the nephron and spilling into the [[urine]]. Dehydration results following the osmotic movement of water into [[urine]], exacerbating the [[acidosis]].
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| ===Alcoholic Ketoacidosis===
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| In [[alcoholic]] ketoacidosis, [[alcohol]] causes dehydration and blocks the first step of [[gluconeogenesis]]. The body is unable to synthesize enough glucose to meet its needs, thus creating an energy crisis resulting in [[fatty acid]] metabolism, and [[ketone body]] formation.
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| == Related Chapters == | | == Related Chapters == |