Hypermagnesemia causes: Difference between revisions
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==Causes== | ==Causes== | ||
Since magnesium is excreted through the [[kidney]]s, [[renal failure]] can result in hypermagnesemia. The most important cause however is suppletion. | * Since magnesium is excreted through the [[kidney]]s, [[renal failure]] can result in hypermagnesemia. The most important cause however is suppletion. | ||
*[[Hemolysis]], magnesium concentration in erythrocytes is approximately three times greater than in serum, therefore hemolysis can increase plasma magnesium. Hypermagnesemia is expected only in massive hemolysis. | |||
*[[Renal insufficiency]], excretion of magnesium becomes impaired when [[creatinine clearance]] falls below 30 ml/min. However, hypermagnesemia is not a prominent feature of renal insufficiency unless magnesium intake is increased. | |||
*Other conditions that can predispose to mild hypermagnesemia are [[diabetic ketoacidosis]], [[adrenal insufficiency]], [[hyperparathyroidism]] and [[lithium]] [[intoxication]]. | |||
==References== | ==References== | ||
Revision as of 16:04, 28 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];
Overview
Causes
- Since magnesium is excreted through the kidneys, renal failure can result in hypermagnesemia. The most important cause however is suppletion.
- Hemolysis, magnesium concentration in erythrocytes is approximately three times greater than in serum, therefore hemolysis can increase plasma magnesium. Hypermagnesemia is expected only in massive hemolysis.
- Renal insufficiency, excretion of magnesium becomes impaired when creatinine clearance falls below 30 ml/min. However, hypermagnesemia is not a prominent feature of renal insufficiency unless magnesium intake is increased.
- Other conditions that can predispose to mild hypermagnesemia are diabetic ketoacidosis, adrenal insufficiency, hyperparathyroidism and lithium intoxication.