Bartter syndrome overview: Difference between revisions
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==Overview== | |||
'''Bartter syndrome''' is a rare inherited defect in the [[thick ascending limb]] of the [[loop of Henle]]. It is characterized by low potassium levels ([[hypokalemia]]), decreased acidity of blood ([[alkalosis]]), and normal to low blood pressure. There are two types of Bartter syndrome: neonatal and classic. A closely associated disorder, [[Gitelman syndrome]], is milder than both subtypes of Bartter syndrome. The condition is named after Dr [[Frederic Bartter]], who first described it in 1962.<ref name=Bartter>{{cite journal | author=Bartter FC, Pronove P, Gill JR Jr, MacCardle RC | title=Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. A new syndrome | journal=Am J Med | year=1962 | pages=811-28 | volume=33 | id=PMID 13969763}} Reproduced in {{cite journal |author=Bartter FC, Pronove P, Gill JR, MacCardle RC |title=Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. A new syndrome. 1962 |journal=J. Am. Soc. Nephrol. |volume=9 |issue=3 |pages=516–28 |year=1998 |pmid=9513916 |doi=}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Nephrology]] | [[Category:Nephrology]] | ||
Revision as of 18:55, 28 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Bartter syndrome is a rare inherited defect in the thick ascending limb of the loop of Henle. It is characterized by low potassium levels (hypokalemia), decreased acidity of blood (alkalosis), and normal to low blood pressure. There are two types of Bartter syndrome: neonatal and classic. A closely associated disorder, Gitelman syndrome, is milder than both subtypes of Bartter syndrome. The condition is named after Dr Frederic Bartter, who first described it in 1962.[1]
References
- ↑ Bartter FC, Pronove P, Gill JR Jr, MacCardle RC (1962). "Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. A new syndrome". Am J Med. 33: 811–28. PMID 13969763. Reproduced in Bartter FC, Pronove P, Gill JR, MacCardle RC (1998). "Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. A new syndrome. 1962". J. Am. Soc. Nephrol. 9 (3): 516–28. PMID 9513916.