Zygomycosis medical therapy: Difference between revisions
Rim Halaby (talk | contribs) (Created page with "__NOTOC__ {{Zygomycosis}} {{CMG}} Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing. ==Overview== ...") |
Rim Halaby (talk | contribs) No edit summary |
||
| Line 8: | Line 8: | ||
==Medical Therapy== | ==Medical Therapy== | ||
If mucormycosis is suspected, prompt [[amphotericin B]] therapy should be administered due to the rapid spread and mortality rate of the disease. Amphotericin B (which works by damaging the [[cell wall]]s of the fungi) is usually administered for a further 4-6 weeks after initial therapy begins to ensure eradication of the infection. [[Posaconazole]] has been shown to be effective against mucormycosis, perhaps more so than amphotericin B, but has not yet replaced it as the standard of care. After administration the patient must then be admitted to surgery for removal of the "[[fungus ball]]". The disease must be monitored carefully for any signs of reemergence.<ref name=HealthAtoZ/> | If mucormycosis is suspected, prompt [[amphotericin B]] therapy should be administered due to the rapid spread and mortality rate of the disease. Amphotericin B (which works by damaging the [[cell wall]]s of the fungi) is usually administered for a further 4-6 weeks after initial therapy begins to ensure eradication of the infection. [[Posaconazole]] has been shown to be effective against mucormycosis, perhaps more so than amphotericin B, but has not yet replaced it as the standard of care. After administration the patient must then be admitted to surgery for removal of the "[[fungus ball]]". The disease must be monitored carefully for any signs of reemergence.<ref name=HealthAtoZ/> | ||
Treatment for skin lesions is traditionally with [[potassium iodide]],<ref>{{cite journal | journal=Ann Trop Paediatr | year=1997 | volume=17 | issue=2 | pages=161–4 | title=Invasive retroperitoneal infection due to ''Basidiobolus ranarum'' with response to potassium iodide—case report and review of the literature | author=Nazir Z, Hasan R, Pervaiz S, Alam M, Moazam F. | id=PMID 9230980 }}</ref> but [[itraconazole]] has also been used successfully.<ref>{{cite journal | title=Invasive gastrointestinal Basidiobolus ranarum infection in an immunocompetent child (brief report) | journal=Ped Infect Dis J | volume=22 | issue=3 | pages=281–82 | year=2003 | |||
| author=Yusuf NW, Assaf HM, Rotowa N | url=http://www.pidj.org/pt/re/pidj/abstract.00006454-200303000-00017.htm;jsessionid=FTfGLBRhv2R67Pf9kryJv3wqjTGmvvMXQpXG4qdjMJZThvwyDQ2L!1671728877!-949856145!8091!-1 }}</ref><ref>{{cite journal | author=Mathew RM, Kumaravel S, Kuruvilla S, ''et al.'' | title=Successful treatment of extensive basidiobolomycosis with oral itraconazole in a child | journal=Int J Dermatol | volume=44 | issue=7 | year=2005 | pages=572–75 }}</ref> | |||
==References== | ==References== | ||
Revision as of 19:46, 2 October 2012
|
Zygomycosis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Zygomycosis medical therapy On the Web |
|
American Roentgen Ray Society Images of Zygomycosis medical therapy |
|
Risk calculators and risk factors for Zygomycosis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Overview
Medical Therapy
If mucormycosis is suspected, prompt amphotericin B therapy should be administered due to the rapid spread and mortality rate of the disease. Amphotericin B (which works by damaging the cell walls of the fungi) is usually administered for a further 4-6 weeks after initial therapy begins to ensure eradication of the infection. Posaconazole has been shown to be effective against mucormycosis, perhaps more so than amphotericin B, but has not yet replaced it as the standard of care. After administration the patient must then be admitted to surgery for removal of the "fungus ball". The disease must be monitored carefully for any signs of reemergence.[1] Treatment for skin lesions is traditionally with potassium iodide,[2] but itraconazole has also been used successfully.[3][4]
References
- ↑
- ↑ Nazir Z, Hasan R, Pervaiz S, Alam M, Moazam F. (1997). "Invasive retroperitoneal infection due to Basidiobolus ranarum with response to potassium iodide—case report and review of the literature". Ann Trop Paediatr. 17 (2): 161&ndash, 4. PMID 9230980.
- ↑ Yusuf NW, Assaf HM, Rotowa N (2003). "Invasive gastrointestinal Basidiobolus ranarum infection in an immunocompetent child (brief report)". Ped Infect Dis J. 22 (3): 281&ndash, 82.
- ↑ Mathew RM, Kumaravel S, Kuruvilla S; et al. (2005). "Successful treatment of extensive basidiobolomycosis with oral itraconazole in a child". Int J Dermatol. 44 (7): 572&ndash, 75.