Torsades de pointes risk factors: Difference between revisions
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Created page with "__NOTOC__ {{Torsades de pointes}} {{CMG}} ==Overview== ==Risk Factors== Factors that are associated with an increased tendency toward torsades de pointes include: * [[Famil..." |
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* Baseline electrocardiographic abnormalities | * Baseline electrocardiographic abnormalities | ||
* Renal or liver failure | * Renal or liver failure | ||
===Clinical Correlation === | |||
# Drugs: [[quinidine]], [[PCA]], [[norpace]], [[amiodarone]], [[phenothiazines]], [[Tricyclic antidepressants]], [[pentamidine]]. | |||
#* with [[quinidine]] majority of the cases occur within one week of initiation, and with therapeutic levels | |||
# Electrolyte imbalances: [[Hypokalemia]], [[hypomagnesemia]], [[hypocalcemia]] | |||
# [[CAD]] | |||
# [[MVP]] | |||
# Variant [[angina]] | |||
# [[Myocarditis]] | |||
# [[Subarachnoid hemorrhage]] | |||
# Congenital QT prolongation | |||
# Liquid protein diets | |||
# [[Hypothyroidism]] | |||
#* because of bradycardia and a prolonged QT syndrome | |||
# Organophosphate poisoning <ref>Chou's Electrocardiography in Clinical Practice Third Edition, pp. 398-409.</ref> <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:194 ISBN 1591032016</ref> | |||
==References== | ==References== |
Revision as of 02:06, 15 October 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Risk Factors
Factors that are associated with an increased tendency toward torsades de pointes include:
- Familial long QT syndrome
- Class IA antiarrhythmics
- Hypomagnesemia
- Hypokalemia
- Hypoxia
- Acidosis
- Heart failure
- Left ventricular hypertrophy
- Slow heart rate
- Female gender
- Baseline electrocardiographic abnormalities
- Renal or liver failure
Clinical Correlation
- Drugs: quinidine, PCA, norpace, amiodarone, phenothiazines, Tricyclic antidepressants, pentamidine.
- with quinidine majority of the cases occur within one week of initiation, and with therapeutic levels
- Electrolyte imbalances: Hypokalemia, hypomagnesemia, hypocalcemia
- CAD
- MVP
- Variant angina
- Myocarditis
- Subarachnoid hemorrhage
- Congenital QT prolongation
- Liquid protein diets
- Hypothyroidism
- because of bradycardia and a prolonged QT syndrome
- Organophosphate poisoning [1] [2]