Atrial septal defect physical examination: Difference between revisions
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=====Murmurs===== | =====Murmurs===== | ||
Several different types of murmur can occur in [[atrial septal defect]]: | |||
=====Rumbling middiastolic murmur===== | |||
* Heard best at the lower left sternal border. | |||
* Heard commonly in large [[left-to-right shunt]]s. | |||
* Occur due to increased flow across the [[tricuspid valve]] | |||
=====Crescendo-decrescendo systolic ejection murmur===== | |||
* Murmur best heard at second intercostal space at the upper left sternal border. | |||
* Heard commonly in moderate-to-large [[left-to-right shunt]]s | |||
* Occur due to increased right ventricular stroke volume and flow across the [[pulmonary artery]]. | |||
=====Midsystolic pulmonary flow or ejection murmur===== | |||
* Heard best at 2nd intercostal space at upper left sternal border. | |||
* Heard commonly in moderate to large left-to-right shunts | |||
* Occur due to increased right ventricular [[stroke volume]] across [[pulmonary outflow tract]] | |||
=====Systolic [[crescendo-decrescendo murmur]]===== | |||
* Audible over the lung fields and is thought to occur from rapid flow through the peripheral [[pulmonary arteries]] | |||
=====Pansystolic mitral regurgitation murmur===== | |||
* Can be heard in [[Atrial septal defect ostium primum|ostium primum]] defects with accompanied [[mitral valve|cleft mitral valve]] or [[Atrial septal defect ostium secundum|secundum defects]] with [[mitral valve prolapse]]. | |||
* High pitched and blowing quality. | |||
* Best heard with diaphragm of stethoscope with patient in left lateral dicubitus position. | |||
* Usually best heard over the apical region with radiation to left axilla and left subscapular area. | |||
* Posterior leaflet dysfunction murmur radiate to sternum or aortic area, anterior leaflet dysfunction murmur radiate to back. | |||
* [[Left-to-right shunt]]ing of blood across the atria does not cause a [[murmur]] at the site of the shunt. This is so, because the pressure gradient between the [[atria]] are not high. | * [[Left-to-right shunt]]ing of blood across the atria does not cause a [[murmur]] at the site of the shunt. This is so, because the pressure gradient between the [[atria]] are not high. | ||
Revision as of 00:12, 18 October 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3] Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [4]
Overview
On physical examination, a patient with an atrial septal defect may present with a crescendo-decrescendo systolic ejection murmur and widely fixed split S2.
Physical examination
The physical findings in an adult with an atrial septal defect depends on:
- Size of defect
- Degree of left-to-right shunt
- Pressure in pulmonary vasculature
- Any associated anomalies for e.g. mitral valve prolapse in ostium primum
Appearance
- Underdevelopment/below-average size for age.
Cardiovascular examination
Inspection
- Precordial bulge- The left-to-right shunting of blood causes right atrial enlargement that can present as a precordial bulge. The precordial bulge can cause a counter development of Harrison's groove that are horizontal depressions along the sixth and seventh costal cartilages at the lower margin of the thorax where the diaphragm attaches to the ribs.
- Precordial lift- An increased left-to-right atrial shunt can cause a hyperdynamic right ventricular flow that can be seen as precordial lift on inspection
Palpation
- Right ventricular impulse- An increased left-to-right atrial shunt can cause a hyperdynamic right ventricular impulse or heave. The heave can be best palpated at the left sternal border or the subxiphoid area.
- Pulmonary artery pulsations - Pulsatile, enlarged pulmonary artery pulsation can be felt at the second left intercostal space. These are more pronounced in patients with large left-to-right shunts. Patients with obstruction to right ventricular outflow have a less dynamic right ventricular impulse and may present with more of a tapping or thrusting quality.
- Thrill - In large left-to-right shunt or the presence of a pulmonic stenosis a thrill can be palpated.
Auscultation
First heart sound, S1
- Best heard at apex
- Can be split. The reason behind the split is that the large volume of diastolic blood flow from right atrium to right ventricle causing forceful contraction of the tricuspid leaflets
Second heart sound S2
- Best heard at second inter-costal space.
- Fixed splitting of the second heart sound (S2).
- It should be evaluated with the patient sitting or standing.
- Commonly seen with large left-to-right shunt and absence of pulmonary hypertension.
- In unaffected individuals, there are respiratory variations in the splitting of the second heart sound (S2). During respiratory inspiration, the negative intrathoracic pressure causes increased blood return into the right side of the heart. The increased blood volume in the right ventricle causes the pulmonic valve to stay open longer during ventricular systole. This causes a normal delay in the P2 component of S2. During expiration, the positive intrathoracic pressure causes decreased blood return to the right side of the heart. The reduced volume in the right ventricle allows the pulmonic valve to close earlier at the end of ventricular systole, causing P2 to occur earlier. In individuals with an atrial septal defect, there is a fixed splitting of S2. Fixed splitting occurs as a result of the extra blood return during inspiration equalized by the intraseptal communication between the left and right atrium allowed by the defect. Fixed splitting of S2 is rare with ASDs in newborns as they have little left-to right shunts.
{{#ev:youtube|5tBk1XuEyuM}}
Murmurs
Several different types of murmur can occur in atrial septal defect:
Rumbling middiastolic murmur
- Heard best at the lower left sternal border.
- Heard commonly in large left-to-right shunts.
- Occur due to increased flow across the tricuspid valve
Crescendo-decrescendo systolic ejection murmur
- Murmur best heard at second intercostal space at the upper left sternal border.
- Heard commonly in moderate-to-large left-to-right shunts
- Occur due to increased right ventricular stroke volume and flow across the pulmonary artery.
Midsystolic pulmonary flow or ejection murmur
- Heard best at 2nd intercostal space at upper left sternal border.
- Heard commonly in moderate to large left-to-right shunts
- Occur due to increased right ventricular stroke volume across pulmonary outflow tract
Systolic crescendo-decrescendo murmur
- Audible over the lung fields and is thought to occur from rapid flow through the peripheral pulmonary arteries
Pansystolic mitral regurgitation murmur
- Can be heard in ostium primum defects with accompanied cleft mitral valve or secundum defects with mitral valve prolapse.
- High pitched and blowing quality.
- Best heard with diaphragm of stethoscope with patient in left lateral dicubitus position.
- Usually best heard over the apical region with radiation to left axilla and left subscapular area.
- Posterior leaflet dysfunction murmur radiate to sternum or aortic area, anterior leaflet dysfunction murmur radiate to back.
- Left-to-right shunting of blood across the atria does not cause a murmur at the site of the shunt. This is so, because the pressure gradient between the atria are not high.
Auscultatory findings in pulmonic regurgitation
- Widely split S2, S3 and S4 can be heard on auscultation. These heart sounds get accentuated with inspiration..
- Low-pitched murmur, best heard along the third or fourth intercostal spaces adjacent to the left sternal border.
- When the pulmonary artery systolic pressure exceeds 70 mm Hg, dilatation of the pulmonary artery ring may then result in Graham-Steell's murmur. This is a high-pitched, blowing decrescendo murmur heard best along the left parasternal region.
Auscultatory findings in pulmonary hypertension
Left-to-right shunt in atrial septal defect causes increased flow through the pulmonary vasculature, which can lead to pulmonary hypertension. This pulmonary hypertension may finally cause increased pressures in the right side of the heart and reversal of the shunt into a right-to-left shunt. Auscultatory findings accompanying pulmonary hypertension are-
- Increased intensity of the pulmonic component of S2, but no fixed splitting
- Fourth heart sound (right ventricular)
- Midsystolic ejection click
- Absence of tricuspid flow murmur
- A holosystolic murmur of tricuspid insufficiency
- Midsystolic pulmonic murmur
- A high pitched pulmonic regurgitation murmur
Extremities
- Cyanosis and clubbing in case Eisenmenger's syndrome develops.
- Deformed carpal bones
- Deformed thumbs
- Holt-Oram syndrome
- Deformed radial bones
Neurologic
Eisenmenger's syndrome
Eisenmenger's syndrome is defined as the process in which a left-to-right shunt in the heart causes increased flow through the pulmonary vasculature, which leads to pulmonary hypertension, which finally causes increased pressures in the right side of the heart and reversal of the shunt into a right-to-left shunt. This right to left shunt causes the patient to become cyanotic. Thus, Eisenmenger's syndrome is said to develop when there is a pulmonary artery disease, [[right-to-left shunt] and cyanosis
General physical examination
Signs of increased right atrial pressure
- Jugular venous pressure may be raised with 'a' wave indicating increased right atrial pressure. A "v" wave indicating development of tricuspid regurgitation may also be seen
- Peripheral edema
- Hepatomegaly
- Ascites
Cardiovascular examination
- Right ventricular heave and thrill
- Murmurs of tricuspid and pulmonic regurgitation