Fungal meningitis medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
* | *The treatment of fungal meningitis, such as cryptococcal meningitis, is a long course of high dose [[Antifungal drug|antifungals]]. The most commonly administered [[Antifungal drug|antifungals]] are [[amphotericin B]] and [[flucytosine]]<ref>{{cite journal |author=Gottfredsson M, Perfect JR |title=Fungal meningitis |journal=Seminars in Neurology |volume=20 |issue=3 |pages=307–22 |year=2000 |pmid=11051295| doi = 10.1055/s-2000-9394}}</ref>. Other [[Antifungal drug|antifungals]] that can be used are miconazole and fluconazole. | ||
*Increased intracranial pressure is a common finding in fungal meningitis. Therefore, it is recommended to do frequent, ideally daily, lumbar punctures to relieve the intracranial pressure.<ref name="pmid15838017">{{cite journal| author=Bicanic T, Harrison TS| title=Cryptococcal meningitis. | journal=Br Med Bull | year= 2004 | volume= 72 | issue= | pages= 99-118 | pmid=15838017 | doi=10.1093/bmb/ldh043 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15838017 }} </ref> | *Increased intracranial pressure is a common finding in [[fungal meningitis]]. Therefore, it is recommended to do frequent, ideally daily, lumbar punctures to relieve the intracranial pressure.<ref name="pmid15838017">{{cite journal| author=Bicanic T, Harrison TS| title=Cryptococcal meningitis. | journal=Br Med Bull | year= 2004 | volume= 72 | issue= | pages= 99-118 | pmid=15838017 | doi=10.1093/bmb/ldh043 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15838017 }} </ref> | ||
==References== | ==References== | ||
Revision as of 03:41, 23 October 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor(s)-in-Chief: Rim Halaby
Overview
Fungal meningitis, such as cryptococcal meningitis, is treated with long courses of high dose antifungals.
Medical Therapy
- The treatment of fungal meningitis, such as cryptococcal meningitis, is a long course of high dose antifungals. The most commonly administered antifungals are amphotericin B and flucytosine[1]. Other antifungals that can be used are miconazole and fluconazole.
- Increased intracranial pressure is a common finding in fungal meningitis. Therefore, it is recommended to do frequent, ideally daily, lumbar punctures to relieve the intracranial pressure.[2]
References
- ↑ Gottfredsson M, Perfect JR (2000). "Fungal meningitis". Seminars in Neurology. 20 (3): 307–22. doi:10.1055/s-2000-9394. PMID 11051295.
- ↑ Bicanic T, Harrison TS (2004). "Cryptococcal meningitis". Br Med Bull. 72: 99–118. doi:10.1093/bmb/ldh043. PMID 15838017.