Aortic dissection laboratory findings: Difference between revisions

	Aortic dissection Microchapters
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Revision as of 01:45, 29 October 2012

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Routine blood work is usually not helpful and should not delay definitive diagnostic studies such as a CT scan and treatment.

Hemolysis can be present as a result of blood in the false lumen.

There has been one report using a smooth muscle myosin heavy chain immunoassay to help diagnose aortic dissection. They report that a level > 10 ng/ml within the first 12h is 90% sensitive and 97% specific. This finding needs to be confirmed in other trials however.
The presence of an elevated CK MB may indicate the presence of concomitant acute myocardial infarction (often a right coronary artery occlusion due to occlusion of the ostium of the RCA by the dissection).

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 ==Biomarker Studies==
-*There has been one report using a smooth muscle [[myosin heavy chain]] immunoassay to help diagnose aortic dissection.  They report that a level > 10 ng/ml within the first 12h is 90% sensitive and 97% specific.  This finding needs to be confirmed in other trials however.
+*There has been one report using a smooth muscle [[myosin]] heavy chain immunoassay to help diagnose aortic dissection.  They report that a level > 10 ng/ml within the first 12h is 90% sensitive and 97% specific.  This finding needs to be confirmed in other trials however.
 *The presence of an elevated [[CK MB]] may indicate the presence of concomitant [[acute myocardial infarction]] (often a [[right coronary artery]] occlusion due to occlusion of the ostium of the [[RCA]] by the dissection).