Keratoconjunctivitis sicca pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
==Pathophysiology== | ==Pathophysiology== | ||
Having dry eyes for a while can lead to tiny [[abrasion]]s on the surface of the eyes. | Having dry eyes for a while can lead to tiny [[abrasion]]s on the surface of the eyes. In advanced cases, the [[epithelium]] undergoes pathologic changes, namely [[squamous metaplasia]] and loss of [[goblet cell]]s. Some severe cases result in thickening of the corneal surface, corneal erosion, punctate keratopathy, [[epithelium|epithelial]] defects, [[corneal ulcer]]ation (sterile and infected), corneal [[neovascularization]], corneal scarring, corneal thinning, and even corneal perforation. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 19:52, 1 November 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Having dry eyes for a while can lead to tiny abrasions on the surface of the eyes. In advanced cases, the epithelium undergoes pathologic changes, namely squamous metaplasia and loss of goblet cells. Some severe cases result in thickening of the corneal surface, corneal erosion, punctate keratopathy, epithelial defects, corneal ulceration (sterile and infected), corneal neovascularization, corneal scarring, corneal thinning, and even corneal perforation.