Keratoconjunctivitis sicca pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
==Pathophysiology== | ==Pathophysiology== | ||
Having dry eyes for a while can lead to tiny [[abrasion]]s on the surface of the eyes.<ref name= | Having dry eyes for a while can lead to tiny [[abrasion]]s on the surface of the eyes.<ref name=Merck-1> | ||
{{cite web | |||
| url = http://www.merck.com/mmhe/sec20/ch230/ch230d.html | |||
| title = Keratoconjunctivitis Sicca | |||
| accessdate = 2006-11-12 | |||
| date = 2003-02-01 | |||
| work = [[Merck Manual of Diagnosis and Therapy|The Merck Manual, Home Edition]] | |||
| publisher = [[Merck & Co.|Merck & Co., Inc.]] | |||
}} | |||
</ref> In advanced cases, the [[epithelium]] undergoes pathologic changes, namely [[squamous metaplasia]] and loss of [[goblet cell]]s. Some severe cases result in thickening of the corneal surface,<ref name=Merck-1/> corneal erosion, punctate keratopathy, [[epithelium|epithelial]] defects, [[corneal ulcer]]ation (sterile and infected), corneal [[neovascularization]], corneal scarring,<ref name=Merck-1/> corneal thinning, and even corneal perforation. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Latest revision as of 20:05, 1 November 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Having dry eyes for a while can lead to tiny abrasions on the surface of the eyes.[1] In advanced cases, the epithelium undergoes pathologic changes, namely squamous metaplasia and loss of goblet cells. Some severe cases result in thickening of the corneal surface,[1] corneal erosion, punctate keratopathy, epithelial defects, corneal ulceration (sterile and infected), corneal neovascularization, corneal scarring,[1] corneal thinning, and even corneal perforation.
References
- ↑ 1.0 1.1 1.2 "Keratoconjunctivitis Sicca". The Merck Manual, Home Edition. Merck & Co., Inc. 2003-02-01. Retrieved 2006-11-12.