Levo-transposition of the great arteries overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [5]

Overview

• levo-Transposition of the great arteries, also commonly referred to as congenitally corrected transposition of the great arteries
• It is an acyanotic heart defect congenital heart defect in which the primary arteries, the aorta and the pulmonary artery are transposed, with the aorta anterior and to the left of the pulmonary artery; and the morphological left and right ventricles are also transposed. Use of the term "corrected" has been disputed by many due to the frequent occurrence of other abnormalities and or acquired disorders in l-TGA patients.
• In segmental analysis, this condition is described as atrioventricular discordance ventricular inversion with ventriculoarterial discordance.
• l-TGA is often referred to simply as transposition of the great arteries(TGA); however, TGA is a more general term which may also refer to dextro-transposition of the great arteries (d-TGA).
• Another term commonly used to refer to both l-TGA and d-TGA is transposition of the great vessels(TGV), although this term can have an even broader meaning than TGA.
• The letter L in the terms l-TGA or L-TGA refers to the a leftward or Levo aorta, versus the normal dextro or rightward aorta.