Acanthocytosis overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Acanthocytosis is a digestive disorder that is characterized by the absence of very low density lipoproteins (VLDL) and chylomicrons in the plasma. Acanthocyte is a general term meaning 'spiny cell'. AKA "spur cell" in more severe cases In human biology and medicine, the term refers to pathological red blood cells, which are coarse and irregularly crenelated resembling many-pointed stars. They are seen on blood films in, among others, lipid abnormalities, liver disease, chorea acanthocytosis, McLeod syndrome and several inherited neurological disorders, such as neuroacanthocytosis.