Neurosyphilis overview: Difference between revisions
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==Overview== | ==Overview== | ||
Neurosyphilis refers to a site of infection involving the [[central nervous system]] (CNS). It may occur at any stage of syphilis. Before the advent of antibiotics, it was typically seen in 25-35% of patients with syphilis. Neurosyphilis is now most common in patients with [[HIV]] infection. Reports of neurosyphilis in HIV-infected persons are similar to cases reported before the HIV [[pandemic]]. The precise extent and significance of neurologic involvement in HIV-infected patients with syphilis, reflected by either laboratory or clinical criteria, have not been well characterized. Furthermore, the alteration of host [[immunosuppression]] by [[antiretroviral drug|antiretroviral therapy]] in recent years has further complicated such characterization. | |||
==References== | ==References== | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Gynecology]] | |||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
[[Category:Bacterial diseases]] | |||
[[Category:Sexually transmitted diseases]] | |||
[[Category:Needs overview]] |
Revision as of 14:47, 20 November 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Neurosyphilis refers to a site of infection involving the central nervous system (CNS). It may occur at any stage of syphilis. Before the advent of antibiotics, it was typically seen in 25-35% of patients with syphilis. Neurosyphilis is now most common in patients with HIV infection. Reports of neurosyphilis in HIV-infected persons are similar to cases reported before the HIV pandemic. The precise extent and significance of neurologic involvement in HIV-infected patients with syphilis, reflected by either laboratory or clinical criteria, have not been well characterized. Furthermore, the alteration of host immunosuppression by antiretroviral therapy in recent years has further complicated such characterization.