Brain ischemia: Difference between revisions
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==Overview== | |||
'''Brain ischemia''' (or '''cerebral ischemia''') is an [[ischemic]] condition where the [[brain]] or parts of the brain do not receive enough [[blood flow]] to maintain normal [[neurological]] function. | '''Brain ischemia''' (or '''cerebral ischemia''') is an [[ischemic]] condition where the [[brain]] or parts of the brain do not receive enough [[blood flow]] to maintain normal [[neurological]] function. | ||
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Cerebral ischemia can be the result of various [[diseases]], or the result of [[arterial]] obstruction such as [[strangulation]]. | Cerebral ischemia can be the result of various [[diseases]], or the result of [[arterial]] obstruction such as [[strangulation]]. | ||
== | ==History and Symptoms== | ||
Similarly to [[cerebral hypoxia]], severe or prolonged cerebral ischemia will result in [[unconsciousness]], [[brain damage]] or [[death]], mediated by the [[ischemic cascade]]. | Similarly to [[cerebral hypoxia]], severe or prolonged cerebral ischemia will result in [[unconsciousness]], [[brain damage]] or [[death]], mediated by the [[ischemic cascade]]. | ||
An extensive review of mechanisms by which ischemia damages the nervous system has been published by Peter Lipton.<ref name="urlIschemic Cell Death in Brain Neurons -- Lipton 79 (4): 1431 -- Physiological Reviews">{{cite web |url=http://physrev.physiology.org/cgi/content/full/79/4/1431 |title=Ischemic Cell Death in Brain Neurons -- Lipton 79 (4): 1431 -- Physiological Reviews |format= |work= |accessdate=}}</ref> | An extensive review of mechanisms by which ischemia damages the nervous system has been published by Peter Lipton.<ref name="urlIschemic Cell Death in Brain Neurons -- Lipton 79 (4): 1431 -- Physiological Reviews">{{cite web |url=http://physrev.physiology.org/cgi/content/full/79/4/1431 |title=Ischemic Cell Death in Brain Neurons -- Lipton 79 (4): 1431 -- Physiological Reviews |format= |work= |accessdate=}}</ref> | ||
==Related | ==Related Conditions== | ||
A related condition is [[subcortical ischemic depression]], also known as [[vascular depression]]. This condition is most commonly seen in elderly depressed patients. Late onset depression is increasingly seen as a distinct variety of depression, and is commonly detected with an MRI. | A related condition is [[subcortical ischemic depression]], also known as [[vascular depression]]. This condition is most commonly seen in elderly depressed patients. Late onset depression is increasingly seen as a distinct variety of depression, and is commonly detected with an MRI. | ||
Revision as of 20:44, 30 November 2012
Brain ischemia | |
MeSH | D002545 |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Brain ischemia (or cerebral ischemia) is an ischemic condition where the brain or parts of the brain do not receive enough blood flow to maintain normal neurological function.
Causes
Cerebral ischemia can be the result of various diseases, or the result of arterial obstruction such as strangulation.
History and Symptoms
Similarly to cerebral hypoxia, severe or prolonged cerebral ischemia will result in unconsciousness, brain damage or death, mediated by the ischemic cascade.
An extensive review of mechanisms by which ischemia damages the nervous system has been published by Peter Lipton.[1]
Related Conditions
A related condition is subcortical ischemic depression, also known as vascular depression. This condition is most commonly seen in elderly depressed patients. Late onset depression is increasingly seen as a distinct variety of depression, and is commonly detected with an MRI.
References
- Chang, Steven; Doty, James; Skirboll, Stephen; Steinberg, Gary. Cerebral ischemia . cgi.stanford.edu. URL last accessed February 26 2006.
- Ramirez, Robert; Gulli, Laith. Encyclopedia of Neurological Disorders: Hypoxia. health.enotes.com. URL last accessed February 26 2006. (PDF format)