Brain tumor overview: Difference between revisions
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==Overview== | ==Overview== | ||
A '''brain tumor''' is any [[cranium|intracranial]] [[tumor]] created by abnormal and uncontrolled [[Mitosis|cell division]], normally either in the [[brain]] itself ([[neuron]]s, [[glia]]l cells ([[astrocyte]]s, [[oligodendrocyte]]s, [[ependymal cell]]s), [[lymph]]atic tissue, [[blood vessel]]s), in the [[cranial nerve]]s ([[myelin]]-producing [[Schwann cell]]s), in the brain envelopes ([[meninges]]), [[skull]], [[pituitary]] and [[pineal gland]], or spread from [[cancer]]s primarily located in other organs ([[metastasis|metastatic tumors]]). Primary (true) brain tumors are commonly located in the [[posterior cranial fossa]] in [[children]] and in the anterior two-thirds of the [[cerebral hemispheres]] in adults, although they can affect any part of the [[brain]]. In the United States in the year 2005, it was estimated that there were 43,800 new cases of brain tumors (Central Brain Tumor Registry of the United States, Primary Brain Tumors in the United States, Statistical Report, 2005 - 2006) <ref name="r1">Greenlee RT, Murray T, Bolden S, Wingo PA. ''Cancer statistics, 2000.'' CA Cancer J Clin 2000;50:7-33. [http://caonline.amcancersoc.org/cgi/reprint/50/1/7.pdf PDF]. PMID 10735013.</ref>, which accounted for 1.4 percent of all cancers, 2.4 percent of all cancer deaths<ref name="r2">[http://www.cancer.org/ American Cancer Society]. Accessed June 2000.</ref>, and 20–25 percent of pediatric cancers<ref name="r2" /><ref>Chamberlain MC, Kormanik PA. ''Practical guidelines for the treatment of malignant gliomas.'' West J Med 1998;168:114-120. PMID 9499745.</ref>. Ultimately, it is estimated that there are 13,000 deaths/year as a result of brain tumors<ref name="r1" />. | A '''brain tumor''' is any [[cranium|intracranial]] [[tumor]] created by abnormal and uncontrolled [[Mitosis|cell division]], normally either in the [[brain]] itself ([[neuron]]s, [[glia]]l cells ([[astrocyte]]s, [[oligodendrocyte]]s, [[ependymal cell]]s), [[lymph]]atic tissue, [[blood vessel]]s), in the [[cranial nerve]]s ([[myelin]]-producing [[Schwann cell]]s), in the brain envelopes ([[meninges]]), [[skull]], [[pituitary]] and [[pineal gland]], or spread from [[cancer]]s primarily located in other organs ([[metastasis|metastatic tumors]]). Primary (true) brain tumors are commonly located in the [[posterior cranial fossa]] in [[children]] and in the anterior two-thirds of the [[cerebral hemispheres]] in adults, although they can affect any part of the [[brain]]. In the United States in the year 2005, it was estimated that there were 43,800 new cases of brain tumors (Central Brain Tumor Registry of the United States, Primary Brain Tumors in the United States, Statistical Report, 2005 - 2006) <ref name="r1">Greenlee RT, Murray T, Bolden S, Wingo PA. ''Cancer statistics, 2000.'' CA Cancer J Clin 2000;50:7-33. [http://caonline.amcancersoc.org/cgi/reprint/50/1/7.pdf PDF]. PMID 10735013.</ref>, which accounted for 1.4 percent of all cancers, 2.4 percent of all cancer deaths<ref name="r2">[http://www.cancer.org/ American Cancer Society]. Accessed June 2000.</ref>, and 20–25 percent of pediatric cancers<ref name="r2" /><ref>Chamberlain MC, Kormanik PA. ''Practical guidelines for the treatment of malignant gliomas.'' West J Med 1998;168:114-120. PMID 9499745.</ref>. Ultimately, it is estimated that there are 13,000 deaths/year as a result of brain tumors<ref name="r1" />. | ||
==Historical Perspective== | |||
Brain tumors can be classified into two main categories: primary and secondary tumors. Primary tumors originate in astrocytes, oligodendrocytes and ependymal cells. Secondary tumors originate in malignant cancers located primarily in other organs. As of 1993, the World Health Oreganization classifies primary brain tumors as the most common. | |||
==References== | ==References== | ||
Revision as of 20:48, 30 November 2012
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Brain tumor Microchapters |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
A brain tumor is any intracranial tumor created by abnormal and uncontrolled cell division, normally either in the brain itself (neurons, glial cells (astrocytes, oligodendrocytes, ependymal cells), lymphatic tissue, blood vessels), in the cranial nerves (myelin-producing Schwann cells), in the brain envelopes (meninges), skull, pituitary and pineal gland, or spread from cancers primarily located in other organs (metastatic tumors). Primary (true) brain tumors are commonly located in the posterior cranial fossa in children and in the anterior two-thirds of the cerebral hemispheres in adults, although they can affect any part of the brain. In the United States in the year 2005, it was estimated that there were 43,800 new cases of brain tumors (Central Brain Tumor Registry of the United States, Primary Brain Tumors in the United States, Statistical Report, 2005 - 2006) [1], which accounted for 1.4 percent of all cancers, 2.4 percent of all cancer deaths[2], and 20–25 percent of pediatric cancers[2][3]. Ultimately, it is estimated that there are 13,000 deaths/year as a result of brain tumors[1].
Historical Perspective
Brain tumors can be classified into two main categories: primary and secondary tumors. Primary tumors originate in astrocytes, oligodendrocytes and ependymal cells. Secondary tumors originate in malignant cancers located primarily in other organs. As of 1993, the World Health Oreganization classifies primary brain tumors as the most common.
References
- ↑ 1.0 1.1 Greenlee RT, Murray T, Bolden S, Wingo PA. Cancer statistics, 2000. CA Cancer J Clin 2000;50:7-33. PDF. PMID 10735013.
- ↑ 2.0 2.1 American Cancer Society. Accessed June 2000.
- ↑ Chamberlain MC, Kormanik PA. Practical guidelines for the treatment of malignant gliomas. West J Med 1998;168:114-120. PMID 9499745.