Hepatitis D overview: Difference between revisions
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==Overview== | ==Overview== | ||
'''Hepatitis D''' is a [[disease]] caused by a small circular [[RNA virus]] ('''Hepatitis delta virus''' or '''hepatitis D virus''', '''HDV'''). HDV is considered to be a [[Satellite (biology)|subviral satellite]] because it can propagate only in the presence of another virus, the [[Hepatitis B|hepatitis B virus (HBV)]]. Transmission of HDV can occur either via simultaneous infection with HBV ([[coinfection]]) or via infection of an individual previously infected with HBV ([[superinfection]]). [http://www.cdc.gov/ncidod/diseases/hepatitis/slideset/hep_d/slide_1.htm] | '''Hepatitis D''' is a [[disease]] caused by a small circular [[RNA virus]] ('''Hepatitis delta virus''' or '''hepatitis D virus''', '''HDV'''). HDV is considered to be a [[Satellite (biology)|subviral satellite]] because it can propagate only in the presence of another virus, the [[Hepatitis B|hepatitis B virus (HBV)]]. Transmission of HDV can occur either via simultaneous infection with HBV ([[coinfection]]) or via infection of an individual previously infected with HBV ([[superinfection]]). [http://www.cdc.gov/ncidod/diseases/hepatitis/slideset/hep_d/slide_1.htm] | ||
Both superinfection and coinfection with HDV results in more severe complications compared to infection with HBV alone. These complications include a greater likelihood of experiencing liver failure in acute infections and a greater likelihood of developing liver cancer in chronic infections. In combination with hepatitis B virus, hepatitis D has the highest mortality rate of all the hepatitis infections of 20%. | Both superinfection and coinfection with HDV results in more severe complications compared to infection with HBV alone. These complications include a greater likelihood of experiencing liver failure in acute infections and a greater likelihood of developing liver cancer in chronic infections. In combination with hepatitis B virus, hepatitis D has the highest mortality rate of all the hepatitis infections of 20%. | ||
==Historical Perspective== | |||
The hepatitis D virus was first reported in mid-1977 by an italian researcher, Mario Rizzetto. <ref>Manuale di Gastroenterologia Unigastro pag. 260 </ref> | |||
==References== | ==References== | ||
Revision as of 19:14, 4 December 2012
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Hepatitis D |
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Diagnosis |
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Treatment |
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Hepatitis D overview On the Web |
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American Roentgen Ray Society Images of Hepatitis D overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hepatitis D is a disease caused by a small circular RNA virus (Hepatitis delta virus or hepatitis D virus, HDV). HDV is considered to be a subviral satellite because it can propagate only in the presence of another virus, the hepatitis B virus (HBV). Transmission of HDV can occur either via simultaneous infection with HBV (coinfection) or via infection of an individual previously infected with HBV (superinfection). [2] Both superinfection and coinfection with HDV results in more severe complications compared to infection with HBV alone. These complications include a greater likelihood of experiencing liver failure in acute infections and a greater likelihood of developing liver cancer in chronic infections. In combination with hepatitis B virus, hepatitis D has the highest mortality rate of all the hepatitis infections of 20%.
Historical Perspective
The hepatitis D virus was first reported in mid-1977 by an italian researcher, Mario Rizzetto. [1]
References
- ↑ Manuale di Gastroenterologia Unigastro pag. 260