Cyclosporiasis pathophysiology: Difference between revisions
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{{Cyclosporiasis}} | {{Cyclosporiasis}} | ||
{{CMG}} | {{CMG}} | ||
==Pathophysiology== | ==Pathophysiology== | ||
[[Image:Cyclosporiasis.gif|300px|left]] | [[Image:Cyclosporiasis.gif|300px|left]] |
Revision as of 14:29, 5 December 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Pathophysiology
When freshly passed in stools, the oocyst is not infective (thus, direct fecal-oral transmission cannot occur; this differentiates Cyclospora from another important coccidian parasite, Cryptosporidium). In the environment , sporulation occurs after days or weeks at temperatures between 22°C to 32°C, resulting in division of the sporont into two sporocysts, each containing two elongate sporozoites . Fresh produce and water can serve as vehicles for transmission and the sporulated oocysts are ingested (in contaminated food or water) . The oocysts excyst in the gastrointestinal tract, freeing the sporozoites which invade the epithelial cells of the small intestine . Inside the cells they undergo asexual multiplication and sexual development to mature into oocysts, which will be shed in stools . The potential mechanisms of contamination of food and water are still under investigation.