Foot-and-mouth disease causes: Difference between revisions
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==Overview== | ==Overview== | ||
Foot-and-mouth disease is caused by FMDV, an [[Aphthovirus]] of the viral family [[Picornaviridae]]. The members of this family are small (25-30 nm), nonenveloped [[icosahedral]] viruses that contain single-stranded [[RNA]] (ribonucleic acid, the viral genetic material). When such a virus comes in contact with a host cell, it binds to a receptor site and triggers a folding-in of the cell membrane. Once the virus is inside the host cell, its protein coat dissolves. New viral [[RNA]] and components of the protein coat are then synthesized in large quantities and assembled to form new viruses. After assembly, the host cell [[lysis|lyses]] (bursts) and releases the new [[viruses]]. | Foot-and-mouth disease is caused by FMDV, an [[Aphthovirus]] of the viral family [[Picornaviridae]]. The members of this family are small (25-30 nm), nonenveloped [[icosahedral]] viruses that contain single-stranded [[RNA]] (ribonucleic acid, the viral genetic material). When such a virus comes in contact with a host cell, it binds to a receptor site and triggers a folding-in of the cell membrane. Once the virus is inside the host cell, its protein coat dissolves. New viral [[RNA]] and components of the protein coat are then synthesized in large quantities and assembled to form new viruses. After assembly, the host cell [[lysis|lyses]] (bursts) and releases the new [[viruses]]. There are seven FMD [[serotype]]s: O, A, C, SAT-1, SAT-2, SAT-3, and Asia-1. These serotypes show some regionality, and the O serotype is most common. | ||
== References == | == References == | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 20:02, 6 December 2012
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Foot-and-mouth disease Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Foot-and-mouth disease is caused by FMDV, an Aphthovirus of the viral family Picornaviridae. The members of this family are small (25-30 nm), nonenveloped icosahedral viruses that contain single-stranded RNA (ribonucleic acid, the viral genetic material). When such a virus comes in contact with a host cell, it binds to a receptor site and triggers a folding-in of the cell membrane. Once the virus is inside the host cell, its protein coat dissolves. New viral RNA and components of the protein coat are then synthesized in large quantities and assembled to form new viruses. After assembly, the host cell lyses (bursts) and releases the new viruses. There are seven FMD serotypes: O, A, C, SAT-1, SAT-2, SAT-3, and Asia-1. These serotypes show some regionality, and the O serotype is most common.