Helicobacter pylori infection overview: Difference between revisions
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==Overview== | ==Overview== | ||
'''''Helicobacter pylori''''' ( | '''''Helicobacter pylori''''' ('''''H. pylori'''''), previously named '''''Campylobacter pyloridis''''', is a [[Gram-negative]], [[microaerophile|microaerophilic]] [[bacterium]] found in the [[stomach]]. It was identified in 1982 by [[Barry Marshall]] and [[Robin Warren]], who found that it was present in patients with chronic [[gastritis]] and [[Peptic ulcer|gastric ulcers]], conditions that were not previously believed to have a [[Microorganism|microbial]] cause. It is also linked to the development of [[duodenum|duodenal]] ulcers and [[stomach cancer]]. However, over 80 percent of individuals infected with the bacterium are [[asymptomatic]] and it has been postulated that it may play an important role in the natural stomach ecology.<ref>{{Cite journal | ||
| last1 = Blaser | first1 = M. J. | | last1 = Blaser | first1 = M. J. | ||
| title = Who are we? Indigenous microbes and the ecology of human diseases | | title = Who are we? Indigenous microbes and the ecology of human diseases | ||
Revision as of 00:58, 7 December 2012
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Helicobacter pylori infection Microchapters |
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Differentiating Helicobacter pylori infection from other Diseases |
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Diagnosis |
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Guideline Recommendation |
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Treatment |
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Case Studies |
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Helicobacter pylori infection overview On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Helicobacter pylori (H. pylori), previously named Campylobacter pyloridis, is a Gram-negative, microaerophilic bacterium found in the stomach. It was identified in 1982 by Barry Marshall and Robin Warren, who found that it was present in patients with chronic gastritis and gastric ulcers, conditions that were not previously believed to have a microbial cause. It is also linked to the development of duodenal ulcers and stomach cancer. However, over 80 percent of individuals infected with the bacterium are asymptomatic and it has been postulated that it may play an important role in the natural stomach ecology.[1]
More than 50% of the world's population harbor H. pylori in their upper gastrointestinal tract. Infection is more prevalent in developing countries, and incidence is decreasing in Western countries. H. pylori's helix shape (from which the generic name is derived) is thought to have evolved to penetrate the mucoid lining of the stomach.[2][3]
References
- ↑ Blaser, M. J. (2006). "Who are we? Indigenous microbes and the ecology of human diseases" (PDF). EMBO Reports. 7 (10): 956–60. doi:10.1038/sj.embor.7400812. PMC 1618379. PMID 17016449.
- ↑ Yamaoka, Yoshio (2008). Helicobacter pylori: Molecular Genetics and Cellular Biology. Caister Academic Pr. ISBN 1-904455-31-X.
- ↑ Brown LM (2000). "Helicobacter pylori: epidemiology and routes of transmission" (PDF). Epidemiol Rev. 22 (2): 283–97. PMID 11218379.