Post-polio syndrome overview: Difference between revisions
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==Overview== | |||
'''Post-polio syndrome''' ('''PPS''') is a condition that affects survivors of [[poliomyelitis]], a [[virus|viral]] [[infection]] of the [[nervous system]], after recovery from an initial paralytic attack of the virus. Typically the symptoms appear 20-40 years after the original infection, at an age of 35 to 60. Symptoms include new or increased [[muscular weakness]], [[Pain and nociception|pain]] in the [[muscle]]s, and [[fatigue (physical)|fatigue]].<ref name=Cashman_2005>{{cite journal |author=Trojan D, Cashman N |title=Post-poliomyelitis syndrome |journal=Muscle Nerve |volume=31 |issue=1 |pages=6-19 |year=2005 |pmid = 15599928}}</ref> | |||
The precise mechanism that causes post-polio syndrome is unknown. It shares many features in common with [[myalgic encephalomyelitis]], a form of [[chronic fatigue syndrome]] that is apparently caused by viral infections, but unlike those disorders it tends to be progressive, and can cause tangible loss of muscle strength. | |||
Treatment generally is limited to supportive measures, primarily [[leg braces]] and energy-saving devices such as powered wheelchairs, plus pain relievers, sleep aids, etc. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Poliomyelitis]] | [[Category:Poliomyelitis]] | ||
[[Category:Motor neuron disease]] | [[Category:Motor neuron disease]] |
Revision as of 17:10, 7 December 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Post-polio syndrome (PPS) is a condition that affects survivors of poliomyelitis, a viral infection of the nervous system, after recovery from an initial paralytic attack of the virus. Typically the symptoms appear 20-40 years after the original infection, at an age of 35 to 60. Symptoms include new or increased muscular weakness, pain in the muscles, and fatigue.[1]
The precise mechanism that causes post-polio syndrome is unknown. It shares many features in common with myalgic encephalomyelitis, a form of chronic fatigue syndrome that is apparently caused by viral infections, but unlike those disorders it tends to be progressive, and can cause tangible loss of muscle strength.
Treatment generally is limited to supportive measures, primarily leg braces and energy-saving devices such as powered wheelchairs, plus pain relievers, sleep aids, etc.