Coccidioidomycosis laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
The fungal infection can be demonstrated by microscopic detection of diagnostic cells in body fluids, exudates, [[sputum]] and [[biopsy]]-tissue. With specific [[nucleotide]] primers ''C.immitis'' [[DNA]] can be amplified by [[PCR]]. It can also be detected in culture by morphological identification or by using molecular probes that hybridize with ''C.immitis'' [[RNA]]. An indirect demonstration of fungal infection can be achieved also by serologic analysis detecting fungal [[antigen]] or host [[antibody]] produced against the fungus. | The fungal infection can be demonstrated by microscopic detection of diagnostic cells in body fluids, exudates, [[sputum]] and [[biopsy]]-tissue. With specific [[nucleotide]] primers ''C.immitis'' [[DNA]] can be amplified by [[PCR]]. It can also be detected in culture by morphological identification or by using molecular probes that hybridize with ''C.immitis'' [[RNA]]. An indirect demonstration of fungal infection can be achieved also by serologic analysis detecting fungal [[antigen]] or host [[antibody]] produced against the fungus. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Pulmonology]] | |||
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[[Category:Fungal diseases]] | |||
[[Category:Biological weapons]] | |||
[[Category:Infectious disease]] | |||
[[Category:Mature chapter]] | |||
[[Category:Disease]] | |||
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Revision as of 20:32, 7 December 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
The fungal infection can be demonstrated by microscopic detection of diagnostic cells in body fluids, exudates, sputum and biopsy-tissue. With specific nucleotide primers C.immitis DNA can be amplified by PCR. It can also be detected in culture by morphological identification or by using molecular probes that hybridize with C.immitis RNA. An indirect demonstration of fungal infection can be achieved also by serologic analysis detecting fungal antigen or host antibody produced against the fungus.