Bartonellosis history and symptoms: Difference between revisions
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==Symptoms== | ==Symptoms== | ||
*Bartonellosis is usually characterized by an [[Acute (medical)|acute]] stage with primarily [[blood vessel|vascular]] effects and a [[chronic (medicine)|chronic]] stage associated with [[dermatology|skin]] symptoms. | *Bartonellosis is usually characterized by an [[Acute (medical)|acute]] stage with primarily [[blood vessel|vascular]] effects and a [[chronic (medicine)|chronic]] stage associated with [[dermatology|skin]] symptoms. | ||
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Revision as of 20:12, 11 December 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Symptoms
- Bartonellosis is usually characterized by an acute stage with primarily vascular effects and a chronic stage associated with skin symptoms.
- In the acute stage (also known as Oroya fever or Fiebre de la Oroya), bartonellosis is a sudden, potentially life-threatening illness associated with high fever and decreased levels of circulating red blood cells (i.e., hemolytic anemia). The acute phase typically lasts two-to-four weeks.
- Peripheral blood smears shows anisomacrocytosis with many bacilli adherent to red blood cells.
- Thrombocytopenia is also seen and can be very severe.
- Neurologic involvement is sometimes seen (neurobartonellosis) and the prognosis in this case is very guarded.
- It can present as spinal meningitis or as paralysis.
- In the acute stage, the most feared complication is fulminant Salmonella superinfection: for this reason chloramphenicol is the preferred antibiotic treatment.
- The chronic manifestation—Verruga Peruana—consists of a benign skin eruption with raised, reddish-purple nodules (angiomatous tumours). Visualization is possible using a silver stain (the Warthin–Starry method).