Bartonellosis history and symptoms: Difference between revisions

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-==Symptoms==
-*Bartonellosis is usually characterized by an [[Acute (medical)|acute]] stage with primarily [[blood vessel|vascular]] effects and a [[chronic (medicine)|chronic]] stage associated with [[dermatology|skin]] symptoms.
-*In the acute stage (also known as Oroya fever or ''Fiebre de la Oroya''), bartonellosis is a sudden, potentially life-threatening illness associated with high [[fever]] and decreased levels of circulating [[red blood cell]]s (i.e., [[hemolytic anemia]]). The acute phase typically lasts two-to-four weeks.
-**[[Peripheral blood smear]]s shows anisomacrocytosis with many [[bacilli]] adherent to [[red blood cells]].
-**[[Thrombocytopenia]] is also seen and can be very severe.
-**Neurologic involvement is sometimes seen (neurobartonellosis) and the [[prognosis]] in this case is very guarded.
-**It can present as spinal [[meningitis]] or as [[paralysis]].
-**In the acute stage, the most feared complication is [[fulminant]] ''[[Salmonella]]'' [[superinfection]]: for this reason [[chloramphenicol]] is the preferred antibiotic treatment.
-*The chronic manifestation—''Verruga Peruana''—consists of a [[benign]] skin eruption with raised, reddish-purple [[nodule]]s ([[angioma|angiomatous tumours]]). Visualization is possible using a [[silver stain]] (the Warthin–Starry method).
 ==References==

Bartonellosis history and symptoms: Difference between revisions

Revision as of 20:14, 11 December 2012

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