Babesiosis medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
The traditional regimen of [[quinine]] and [[clindamycin]] is often poorly tolerated; recent evidence suggests that a regimen of [[atovaquone]] and [[azithromycin]] can be equally effective <ref name=Krause>{{cite journal | author = Krause P, Lepore T, Sikand V, Gadbaw J, Burke G, Telford S, Brassard P, Pearl D, Azlanzadeh J, Christianson D, McGrath D, Spielman A | title = Atovaquone and azithromycin for the treatment of babesiosis | journal = N Engl J Med | volume = 343 | issue = 20 | pages = 1454-8 | year = 2000 | id = PMID 11078770}}</ref>. | The traditional regimen of [[quinine]] and [[clindamycin]] is often poorly tolerated; recent evidence suggests that a regimen of [[atovaquone]] and [[azithromycin]] can be equally effective <ref name=Krause>{{cite journal | author = Krause P, Lepore T, Sikand V, Gadbaw J, Burke G, Telford S, Brassard P, Pearl D, Azlanzadeh J, Christianson D, McGrath D, Spielman A | title = Atovaquone and azithromycin for the treatment of babesiosis | journal = N Engl J Med | volume = 343 | issue = 20 | pages = 1454-8 | year = 2000 | id = PMID 11078770}}</ref>. In life-threatening cases, exchange [[transfusion]] is performed. In this procedure, the infected red blood cells are removed and replaced with fresh ones. | ||
In life-threatening cases, exchange [[transfusion]] is performed. In this procedure, the infected red blood cells are removed and replaced with fresh ones. | |||
==References== | ==References== | ||
Revision as of 21:30, 12 December 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Most cases of babesiosis resolve without any specific treatment. For ill patients, treatment is usually a two-drug regimen.
Medical Therapy
The traditional regimen of quinine and clindamycin is often poorly tolerated; recent evidence suggests that a regimen of atovaquone and azithromycin can be equally effective [1]. In life-threatening cases, exchange transfusion is performed. In this procedure, the infected red blood cells are removed and replaced with fresh ones.
References
- ↑ Krause P, Lepore T, Sikand V, Gadbaw J, Burke G, Telford S, Brassard P, Pearl D, Azlanzadeh J, Christianson D, McGrath D, Spielman A (2000). "Atovaquone and azithromycin for the treatment of babesiosis". N Engl J Med. 343 (20): 1454–8. PMID 11078770.